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ProteomicsIdentification of di-Boron cleavage events at Dha residues on recombinant protein in e.coli lysate
Neurokinin-A (NKA) is only active when its C-terminus is amidated. B2(OH2) is thought to interact with Dha and cleave the peptide, leaving the amide on the C-terminus of the left-hand peptide. PeptideID MS/MS experiment was performed in e.coli lysate with overevpressed recombinant NKA-eH3 to prove d...
ORGANISM(S): Escherichia coli 
2022-05-19 | PXD030233 | Pride
Chemical cleavage Dha Amidated c-term 
ProteomicsPre-assembly of biomolecular condensate seeds drives RSV replication
During infection many RNA viruses, including respiratory syncytial virus (RSV), form specialized biomolecular condensates, viral factories (VFs), where viral transcription and replication occur1-4. Paradoxically, high protein concentrations are typically required for condensate nucleation5, yet atta...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD070991 | Pride
Ascend Phospho-proteomics Human Immunoprecipitation Rsv 
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