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ProteomicsMulti-omics analysis combined with the Nephroseq database reveals that FN1 and three other genes are closely related to renal function in diabetic nephropathy.
Diabetic nephropathy is a serious late chronic complication of type 2 diabetes and a major cause of end-stage renal disease. In order to better understand the molecular mechanisms of kidney lesions, we examined the mRNA and protein levels of mouse kidney to reveal the changes occurring in the kidney...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-10-20 | PXD058790 | Pride
Proteomics Transcriptomics Liraglutide Type 2 diabetes Empagliflozin Diabetic nephropathy 
MetabolomicsLsr2, a novel cyclic di-GMP receptor, regulate the synthesis of keto-mycolic acid and control biofilm formation in mycobacteria

Cyclic di-GMP (c-di-GMP) is a well-known second messenger that plays a key role in many physiological processes in bacteria. The synthesis of lipids is essential for bacterial biofilm formation. However, whether c-di-GMP signaling modulates the synthesis of lipid and further regulates biofilm for...

2023-12-12 | MTBLS7053 | MetaboLights
TranscriptomicsRNA-seq of retinal organoids derived from RPGR patient-, control- and mutation-corrected-iPSC at different developmental stages
Retinitis pigmentosa (RP) is an irreversible and inherited retinopathy. RPGR mutations are the most common causes of this disease. It remains challenging to decipher the mechanism of RPGR mutation because of the lack of appropriate study models. The substitution of patient-specific diseased retina w...
ORGANISM(S): Homo sapiens 
2020-02-01 | E-MTAB-6490 | biostudies-arrayexpress
UnknownChanges of brain structure and structural covariance networks in Parkinson's disease with different sides of onset.
Not available
S-EPMC12037599 | biostudies-literature
UnknownCase report of ventricular tachycardia simulation facilitated ablation for refractory ventricular arrhythmia post-myocardial infarction: aiming before firing.
Not available
S-EPMC12396111 | biostudies-literature
MetabolomicsAltered metabolome and microbiome features provide clues in understanding irritable bowel syndrome and depression comorbidity

Irritable bowel syndrome (IBS) is one of the functional gastrointestinal disorders characterized by chronic and/or recurrent symptoms of abdominal pain and irregular defecation. Changed gut microbiota has been proposed to mediate IBS; however, contradictory results exist, and IBS-specific microbi...

2021-12-01 | MTBLS2774 | MetaboLights
UnknownCarnosol attenuates Acinetobacter baumannii virulence by interfering with indole-mediated quorum sensing.
Not available
S-EPMC12269709 | biostudies-literature
UnknownA nomogram for enhanced risk stratification for predicting cervical lymph node metastasis in papillary thyroid carcinoma patients.
Not available
S-EPMC11436574 | biostudies-literature
UnknownInsufficient ventilation led to a probable long-range airborne transmission of SARS-CoV-2 on two buses.
Not available
S-EPMC8487323 | biostudies-literature
UnknownThe Decade-Long Chinese Methadone Maintenance Therapy Yields Large Population and Economic Benefits for Drug Users in Reducing Harm, HIV and HCV Disease Burden.
Not available
S-EPMC6861367 | biostudies-literature
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