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Antiretroviral therapy (ART) prevents HIV-1 onward transmission and disease progression, leading to excellent prognosis people living with HIV-1 (PWH). However, significant side effects, complications and impaired immune reconstitution still persist along with ART. We aimed to profile proteome chang...
ORGANISM(S): Homo Sapiens 
2022-03-08 | PXD045070 |
Three groups of cells, including the control group, the senescent cells group, and the DMC-treated senescent cells group
ORGANISM(S): Homo Sapiens 
2023-11-23 | PXD047192 |
Molecular mechanisms of HIV-1 latency have been studied extensively to achieve a functional cure for the acquired immunodeficiency syndrome (AIDS). To develop more promising latency-reversing agents (LRAs) to efficiently reactivate the latent reservoir which is subsequently eliminated by immune surv...
ORGANISM(S): Homo Sapiens 
2022-01-14 | PXD031011 |
Pediatric sepsis is a leading cause of mortality in children across the world. Within pediatric sepsis, how developmental age-specific host immune response impact on the occurrence and development of pediatric sepsis is still unknown, especially between infants and toddlers, which were the major sus...
ORGANISM(S): Homo sapiens (Human) 
2021-11-01 | PXD026656 | Pride
Many chemotherapies are effective against cancers that display high levels of genome instability by disrupting or overwhelming the DNA damage response to induce cell death. PARP inhibitors (PARPi) exploit this vulnerability by stalling DNA repair particularly in homologous recombination (HR)-deficie...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-12-06 | MSV000100135 | MassIVE
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