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Brain exposure of systemically administered biotherapeutics is highly restricted by the blood-brain barrier (BBB). Here, we report the engineering and characterization of a BBB transport vehicle targeting the CD98 heavy chain (CD98hc or SLC3A2) of heterodimeric amino acid transporters (TV^CD98hc). T...
ORGANISM(S): Homo sapiens (Human) 
2023-07-31 | PXD044159 | Pride
This submission is associated with a paper by Hesketh et al. that identifies the GATOR-Rag GTPase pathway as a negative regulator of mTORC1 activation by lysosome-derived amino acids.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-07-30 | MSV000084159 | MassIVE
This submission consists of the mass spectrometry raw files for the manuscript by So et al. (Kinase Networks in TRAIL induced apoptosis). This submission contains files for the data presented as supplementary tables 5 (interaction network of 104 protein kinases in DLD-1 cells) acquired on a QSTAR E...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-01-09 | MSV000078989 | MassIVE
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