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MetabolomicsDesign of Experiments for Maximizing T cell endpoints
Not available
ORGANISM(S): Homo sapiens 
ST001476 | MetabolomicsWorkbench
MetabolomicsA Taguchi Design of Experiments Approach for Untargeted Metabolomics Sample Preparation Optimization
Not available
ORGANISM(S): Caenorhabditis elegans 
ST002046 | MetabolomicsWorkbench
TranscriptomicsExperimental analysis of oligonucleotide microarray design criteria to detect deletions by CGH
BACKGROUND: Microarray comparative genomic hybridization (CGH) is currently one of the most powerful techniques to measure DNA copy number in large genomes. In humans, microarray CGH is widely used to assess copy number variants in healthy individuals and copy number aberrations associated with var...
ORGANISM(S): Homo sapiens 
2008-07-26 | E-GEOD-12208 | biostudies-arrayexpress
ProteomicsUSING DESIGN OF EXPERIMENTS (DoE) TO OPTIMIZE PERFORMANCE AND STABILITY OF BIOMIMETIC CELL MEMBRANE-COATED NANOSTRUCTURES FOR CANCER THERAPY
The present study aimed to develop and optimize cell derived membrane-coated nanostructures by applying a design of experiments (DoE) to improve the therapeutic index by homotypic targeting in cancer cells. The protein composition of the extracted cell membrane from tumoral cells were assessed by ma...
ORGANISM(S): Homo sapiens (Human) 
2023-01-31 | PXD039270 | Pride
Cell membrane coating technology  mass spectrometry-based proteomics  biomimetic systems  stability  design of experiments  homotypic recognition  glioblastoma  temozolomide drug. 
TranscriptomicsAnalysis and design of RNA sequencing experiments for identifying mRNA isoform regulation
Through alternative splicing, most human genes express multiple isoforms that may have distinct or even antagonistic functions. To infer isoform regulation based on data from high-throughput sequencing of cDNA fragments (RNA-Seq), we have developed MISO, a computational model that estimates the expr...
ORGANISM(S): Homo sapiens 
2010-11-07 | E-GEOD-23694 | biostudies-arrayexpress
GenomicsAnalysis and design of RNA sequencing experiments for identifying mRNA isoform regulation
Analysis and design of RNA sequencing experiments for identifying mRNA isoform regulation
PRJNA130865 | ENA
ProteomicsDefinitive Screening Design to Improve Data-Independent MS Analysis of Neuropeptides
A definitive screening design was used to systematically optimize a DIA workflow for crustacean neuropeptide quantitation. We were able to assess several parameters for their effect on increasing quantifiable neuropeptides and predict the optimal value for these parameters.
ORGANISM(S): Callinectes sapidus 
2023-05-10 | PXD038520 | Pride
Design of experiments Neuropeptides Label-free quantitation Library-free 
ProteomicsTMTpro: Design and initial evaluation of a novel Proline-based isobaric 16-plex Tandem Mass Tag reagent set
The design and synthesis of a novel proline-reporter-based isobaric Tandem Mass Tag 16 tag set (TMTpro) was carried out and the data uploaded here is a comparison of the performance of the new TMTpro tags with the current commercially available dimethylpiperidine-reporter-based TMT10/11 reagents. Da...
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) Rattus norvegicus (Rat) 
2019-11-25 | PXD014750 | Pride
Tmt Tmtpro 
ProteomicsEnhancing glycopeptide annotation and glycan localization using the EAD implementation of hot electron capture dissociation through a multiplexed parallel reaction monitoring design of experiment
We present an optimized electron activated dissociation (EAD) methodology for liquid chromatography-tandem mass spectrometry (LC-MS/MS) based characterization of N- and O-glycopeptides. Recombinant human erythropoietin (rhEPO) was used as a model glycoprotein in this study. Applying a full factorial...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2025-10-23 | PXD063177 | Pride
Glycoproteomics Parallel reaction monitoring Electron activated dissociation Design of experiments Lc-ms/ms 
MetabolomicsMetabolomics analysis of the toxic effects of the production of lycopene and its precursors
Using cells as microbial factories enables highly specific production of chemicals with many advantages over chemical syntheses. A number of exciting new applications of this approach are in the area of precision metabolic engineering, which focuses on improving the specificity of target production....
2021-02-11 | MTBLS642 | MetaboLights
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