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UnknownDeubiquitylases in developmental ubiquitin signaling and congenital diseases.
Not available
S-EPMC7862630 | biostudies-literature
TranscriptomicsDzip3 regulates developmental genes in mouse embryonic stem cells by reorganizing 3D chromatin conformation [RNA-seq]
In mouse embryonic stem cells (mES cells), ubiquitylation of histone H2A lysine 119 represses a large number of developmental genes and maintains mES cell pluripotency. It has been suggested that a number of H2A ubiquitin ligases as well as deubiquitylases and related peptide fragments contribute to...
ORGANISM(S): Mus musculus 
2015-12-08 | E-GEOD-71882 | biostudies-arrayexpress
GenomicsDzip3 regulates developmental genes in mouse embryonic stem cells by reorganizing 3D chromatin conformation [ChIP-seq]
In mouse embryonic stem cells (mES cells), ubiquitylation of histone H2A lysine 119 represses a large number of developmental genes and maintains mES cell pluripotency. It has been suggested that a number of H2A ubiquitin ligases as well as deubiquitylases and related peptide fragments contribute to...
ORGANISM(S): Mus musculus 
2015-12-08 | E-GEOD-71883 | biostudies-arrayexpress
UnknownAssessing the Suitability of Deubiquitylases As Substrates For Targeted Protein Degradation.
Not available
S-EPMC12259181 | biostudies-literature
UnknownUsp5, Usp34, and Otu1 deubiquitylases mediate DNA repair in Drosophila melanogaster.
Not available
S-EPMC8990000 | biostudies-literature
ProteomicsGIGANTEA recruits deubiquitylases, UBP12 and UBP13, to regulate accumulation of the ZTL photoreceptor complex
ZEILUPE (ZTL), a blue light photoreceptor with E3 ubiquitin ligase activity, communicates end-of-day light conditions to the circadian clock. To function properly, ZTL protein must accumulate but not destablilize target clock transcription factors before dusk, while in the dark ZTL mediates degradat...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-08-22 | PXD014636 | Pride
Deubiquitylases Arabidopsis Gigantea Circadian clock Ubp Zeitlupe 
UnknownSchlafen 12 Interaction with SerpinB12 and Deubiquitylases Drives Human Enterocyte Differentiation.
Not available
S-EPMC6123821 | biostudies-literature
UnknownSpecificity profiling of deubiquitylases against endogenously generated ubiquitin-protein conjugates.
Not available
S-EPMC11260241 | biostudies-literature
ProteomicsUsp25-Erlin1/2 activity limits cholesterol flux to trigger TLR3 responses and restrict a broad range of viruses
Reprogramming lipid metabolic pathways is a critical feature of activating immune responses to infection. However, how these reconfigurations are regulated, particularly during virus infections are poorly understood. Our previous screen to identify cellular deubiquitylases activated during influenza...
ORGANISM(S): Homo sapiens (Human) Influenza A virus 
2026-02-09 | PXD034797 | Pride
Deubiquitylases Lipid metabolism Interaction proteomics Antiviral immunity 
GenomicsDzip3 regulates developmental genes in mouse embryonic stem cells by reorganizing 3D chromatin conformation [ChIP-seq]
In mouse embryonic stem cells (mES cells), ubiquitylation of histone H2A lysine 119 represses a large number of developmental genes and maintains mES cell pluripotency. It has been suggested that a number of H2A ubiquitin ligases as well as deubiquitylases and related peptide fragments contribute to...
ORGANISM(S): Mus musculus 
2015-12-08 | GSE71883 | GEO
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