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TranscriptomicsCommon neuroinflammatory pathways in neurodegenerative diseases
Neurodegenerative diseases of the central nervous system are characterised by pathogenetic cellular and molecular changes in specific areas of the brain that lead to the dysfunction and/or loss of explicit neuronal populations. Despite exhibiting different clinical profiles and selective neuronal lo...
ORGANISM(S): Homo sapiens 
2011-01-29 | E-GEOD-26927 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse mammary cell subpopulations isolated by flow cytometry, on the basis of staining with antibodies against CD45, CD49f, Sca-1 and the 33A10 antigen
We have carried out microarray-based gene expression analysis of cell subpopulations isolated by flow cytometry, on the basis of staining with antibodies against CD45, CD49f, Sca-1 and the 33A10 antigen, from freshly prepared mouse mammary glands. RNA isolated from cell populations was co-hybridised...
ORGANISM(S): Mus musculus 
2007-11-20 | E-MEXP-423 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of heart tissue from rats kept in normoxic or hypoxic conditions
Animal models of right ventricular hypertrophy. 48 male Wistar rats (10 weeks, weight approximately 290 grams) were divided into two groups of 24 animals. Each group was divided into subgroups of six animals. Four subgroups were maintained at hypobaric, hypoxic pressure. Four subgroups were maintain...
ORGANISM(S): Rattus norvegicus 
2010-08-18 | E-MEXP-2863 | biostudies-arrayexpress
TranscriptomicsmRNA-cardiocirculatory
90K Combimatrix gene expression microarrays were composed by 17,048 replicated probes and 963 not replicated specific for the Ensembl (Ver. 56) Transcripts (protein coding + pseudogenes + retrotransposed elements), 11,363 replicated probes specific for the UniGene clusters (Ver. 38) of length compri...
ORGANISM(S): Sus scrofa 
2014-04-30 | E-MTAB-1941 | biostudies-arrayexpress
TranscriptomicsIdentification of exercise-related genes in mice exposed to cigarette smoke
Cigarette smoke (CS) is the major risk factor for COPD and is linked to cardiopulmonary dysfunction. Exercise training, as part of pulmonary rehabilitation, is recommended for all COPD patients. It has several physiological benefits, but the involved mechanisms remain poorly defined. Here, we employ...
ORGANISM(S): Mus musculus 
2022-11-04 | E-MTAB-12256 | biostudies-arrayexpress
UnknownTwelve Years of Drug Prioritization to Help Accelerate Disease Modification Trials in Parkinson's Disease: The International Linked Clinical Trials Initiative.
Not available
S-EPMC11191436 | biostudies-literature
TranscriptomicsTranscription profiling of heart left ventricles from 15 week old inbred COP, DA, and F1(COP x DA) offspring with respect to aerobic running capacity (low, high, and intermediate performers respectively)
We used high density oligonucleotide arrays to measure the relative expression levels of ~27,000 probe sets in the left ventricles of inbred rat strains; DA (high performing), Copenhagen (COP, low performing), as well as F1(COPxDA) rats bred from these tw
ORGANISM(S): Rattus norvegicus 
2007-09-13 | E-GEOD-1795 | biostudies-arrayexpress
UnknownPrecompetitive Consensus Building to Facilitate the Use of Digital Health Technologies to Support Parkinson Disease Drug Development through Regulatory Science.
Not available
S-EPMC7768153 | biostudies-literature
UnknownTreatment Selection and Prioritization for the EJS ACT-PD MAMS Trial Platform.
Not available
S-EPMC12273612 | biostudies-literature
TranscriptomicsIntroducing synthetic thermostable RNase inhibitors in single-cell RNA-seq
Single-cell RNA-sequencing (scRNAseq) is revolutionizing biomedicine, propelled by advances in methodology, ease of use, and cost reduction of library preparation. Over the past decade, there have been remarkable technical improvements in most aspects of single-cell transcriptomics. Yet, there has b...
ORGANISM(S): Mus musculus 
2024-07-29 | E-MTAB-13873 | biostudies-arrayexpress
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