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TranscriptomicsTranscription profiling of mouse PRIMARY keratinocytes infected WITH a retrovirus carryng THE DNp63alpha isform fused TO THE estrogene receptor domain AND induced WITH tamoxifen
Genome-wide identification of bona fide targets of transcription factors in mammalian cells is still a challenge. We present a novel integrated computational and experimental approach to identify direct targets of a transcription factor. This consists in measuring time-course (dynamic) gene expressi...
ORGANISM(S): Mus musculus 
2008-04-05 | E-GEOD-10562 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse primary keratinocytes treated with Tamoxifen
Genome-wide identification of bona fide targets of transcription factors in mammalian cells is still a challenge. We present a novel integrated computational and experimental approach to identify direct targets of a transcription factor. This consists in measuring time-course (dynamic) gene expressi...
ORGANISM(S): Mus musculus 
2008-04-05 | E-GEOD-10563 | biostudies-arrayexpress
TranscriptomicssiRNA silencing of p63 (trp63) in human primary keratinocytes via siRNA oligo transfection.
Genome-wide identification of bona fide targets of transcription factors in mammalian cells is still a challenge. We present a novel integrated computational and experimental approach to identify direct targets of a transcription factor. This consists in measuring time-course (dynamic) gene expressi...
ORGANISM(S): Mus musculus 
2008-04-06 | E-GEOD-10564 | biostudies-arrayexpress
UnknownIn-vivo real-time control of protein expression from endogenous and synthetic gene networks.
Not available
S-EPMC4022480 | biostudies-literature
TranscriptomicsTranscription profiling of pigment cells in the tunicate Ciona intestinalis to study pigment cell specification within Central Nervous System
Its known that FGF signaling induces pigment cell precursors formation. We perturbed the endogenous FGF signaling cascade by using a dominant-negative form of the unique Ci-FGF receptor (FGFRDN) and a constitutively active form of Ci-Ets1/2 (Ets:Vp16), a transcriptional effector of FGF/MAP Kinase ca...
ORGANISM(S): Ciona intestinalis 
2014-07-14 | E-MTAB-2759 | biostudies-arrayexpress
UnknownEnhanced recovery after bariatric surgery: a comprehensive survey-based analysis of ERABS actual clinical implementation in Italian bariatric centers.
Not available
S-EPMC12540566 | biostudies-literature
MetabolomicsDissection of metabolic reprogramming in polycystic kidney disease reveals coordinated rewiring of bioenergetic pathways
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a genetic disorder caused by loss-of-function mutations in PKD1 or PKD2. Increased glycolysis is a prominent feature of the disease, but how it impacts on other metabolic pathways is unknown. Here, we present an analysis of mouse Pkd1 mutant ce...
2019-06-07 | MTBLS677 | MetaboLights
UnknownAmyloid-β 11C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials.
Not available
S-EPMC4553028 | biostudies-literature
TranscriptomicsId proteins synchronize stemness and anchorage to the niche of neural stem cells
Stem cell functions require activation of stem cell-intrinsic transcriptional programs as well as intimate extracellular interactions with a niche microenvironment. How the core pluripotency transcriptional machinery controls residency of stem cells in the niche microenvironment is unknown. Here we ...
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-36488 | biostudies-arrayexpress
UnknownComparison of "IN-REC-SUR-E" and LISA in preterm neonates with respiratory distress syndrome: a randomized controlled trial (IN-REC-LISA trial).
Not available
S-EPMC11218154 | biostudies-literature
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