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MetabolomicsMulti-omic Molecular Characterization and Diagnostic Biomarkers for Occult Hepatitis B Infection and HBsAg-Positive Hepatitis B Infection

BACKGROUND: The pathological and physiological characteristics between HBsAg-positive HBV infection and occult hepatitis B infection (OBI) are currently unclear. This study aimed to explore the immune microenvironment in the peripheral circulation of OBI patients through integration of proteomic ...

2024-11-05 | MTBLS11406 | MetaboLights
MetabolomicsDiagnostic Potential of Plasma IgG N-glycans in Discriminating Thyroid Cancer from Benign Thyroid Nodules and Healthy Controls

BACKGROUND: Novel biomarkers are urgently needed to distinguish between benign and malignant thyroid nodules and detect thyroid cancer in the early stage. The associations between serum IgG N-glycosylation and thyroid cancer risk have been revealed. We aimed to explore the potent...

2021-09-01 | MTBLS2935 | MetaboLights
MetabolomicsThe genetic origin of evolidine, the first cyclopeptide discovered in plants, and related orbitides

Cyclic peptides are reported to have antibacterial, antifungal and other bioactivities. Orbitides are a class of cyclic peptide that are small, head-to-tail cyclized, composed of proteinogenic amino acids, and lack disulfide bonds; they are also known in several genera of the plant family Rutacea...

2020-10-14 | MTBLS1963 | MetaboLights
ProteomicsIdentification of type strain-specific diagnostic peptides of the Bacillus cereus group
The Bacillus cereus group consists of eight very closely related species and comprises both harmless and human pathogenic species. Yet, methods to rapidly and accurately distinguish these species are currently lacking as we demonstrate that classical matrix-assisted laser desorption ionization-time ...
ORGANISM(S): Bacillus cereus (strain ATCC 14579 / DSM 31) Bacillus weihenstephanensis NBRC 101238 = DSM 11821 Bacillus toyonensis BCT-7112 Bacillus thuringiensis serovar berliner ATCC 10792 Bacillus pseudomycoides DSM 12442 Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98) Bacillus mycoides DSM 2048 
2018-02-07 | PXD003669 | Pride
Bacillus cereus group Type strains Diagnostic peptides Lc-ms/ms 
ProteomicsProteotyping of SARS-CoV-2 viral peptides in nasal swab simili
Detection by tandem mass spectrometry of a specific subset of SARS-CoV-2 viral peptides to illustrate the potential of shotgun proteomics for clinical diagnostic.
ORGANISM(S): Betacoronavirus Sp. (ncbitaxon:1928434) 
2020-10-02 | MSV000086229 | MassIVE
UnknownIdentifying diagnostic peptides for lyme disease through epitope discovery.
Not available
S-EPMC96025 | biostudies-literature
ProteomicsSerum Peptidome: Diagnostic Window into Pathogenic Processes following Occupational Exposure to Carbon Nanomaterials
Growing industrial use of carbon nanotubes and nanofibers (CNT/F) warrants consideration of human health outcomes. CNT/F produces pulmonary, cardiovascular, and other toxic effects in animals, with significant augmentation of bioactive circulating peptides, the serum peptidome. While epidemiology am...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-04-26 | MSV000087305 | MassIVE
TranscriptomicsDifferent gene expressions in root tips between CLE10 and CLE25 treatment
Cell–cell communication is critical for tissue and organ development. In plants, secretory CLAVATA3/EMBRYO SURROUNDING REGION-related (CLE) peptides function as intercellular signaling molecules in various aspects of tissue development. However, little is known about intracellular signaling pathways...
ORGANISM(S): Arabidopsis thaliana 
2010-09-03 | E-GEOD-19978 | biostudies-arrayexpress
ProteomicsSystematic characterization of 21 post-translational modification using synthetic peptides
The data presented in this study in the - context of the ProteoemTools project - is based on the synthesis of about 5000 synthetic peptides carrying 21 different post-translational modifications to systematically characterize their chromatographic and mass spectrometric properties using multimodal L...
ORGANISM(S): Homo sapiens (Human) 
2018-06-04 | PXD009449 | Pride
Post-translational modification Acetylation Immonium ion Ptm Proteometools Synthetic standard Phosphorylation Diagnostic ion Neutral loss Synthetic peptides 
TranscriptomicsA genomic approach highlights common and diverse effects and determinants of susceptibility on the yeast Saccharomyces cerevisiae exposed to distinct antimicrobial peptides
The mechanism of action of antimicrobial peptides (AMPs) was initially correlated with peptide membrane permeation properties. However, recent evidences indicate that action of a number of AMPs is more complex and involves specific interactions at cell envelopes or with intracellular targets. In thi...
ORGANISM(S): Saccharomyces cerevisiae 
2010-11-11 | E-GEOD-25279 | biostudies-arrayexpress
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