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TranscriptomicsIntegrative Molecular Concepts Modeling of Prostate Cancer Progression
Using laser capture microdissection to isolate over 100 specific cell populations, we report the profiling of prostate cancer progression from benign epithelium to metastatic disease. By analyzing these expression signatures in the context of over 15,000 â??molecular conceptsâ??, or sets of biologic...
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-6099 | biostudies-arrayexpress
TranscriptomicsGlobal Transcriptional Analysis of Spontaneous Sakacin P-Resistant Mutant Strains of Listeria monocytogenes during Growth on Different Sugars
Subclass IIa bacteriocins have strong antilisterial activity and can control the growth of Listeria monocytogenes in food. However, L. monocytogenes may develop resistance towards such bacteriocins. In this follow-up study, the transcriptomes of a high level (L502-1) and a low level (L502-6) spontan...
ORGANISM(S): Listeria monocytogenes 
2011-04-15 | E-BUGS-110 | biostudies-arrayexpress
TranscriptomicsPhysiology and genetic activity of Listeria monocytogenes during multi-hurdle stress induced cell death
The physiological basis of the hypothesis that temperature is the primary governing factor of bacterial cell inactivation under otherwise non-growth permissive conditions was investigated. Application of simultaneous low pH (pH 3.5) and low water activity (aw = 0.9; 2.5 M NaCl) conditions, applied t...
ORGANISM(S): Listeria monocytogenes 
2010-06-20 | E-GEOD-18796 | biostudies-arrayexpress
UnknownFurther evidence for the involvement of EFL1 in a Shwachman-Diamond-like syndrome and expansion of the phenotypic features.
Not available
S-EPMC6169826 | biostudies-literature
TranscriptomicsExpression Profiling to Identify Novel Desiccation Response Transcripts from Tortula ruralis gametophytes
In this study we have tried to utilize the unique aspects of the T. ruralis response to desiccation and rehydration to design a strategy to identify rehydrins that are of low abundance and perhaps completely novel to the desiccated or rehydration transcriptomes. We have constructed two Subtractive S...
ORGANISM(S): Syntrichia ruralis 
2010-05-06 | E-GEOD-13680 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse CMS4 and CMS4-met cell lines after IFNgamma treatment
The CMS4 sarcoma, kindly provided by A. DeLeo (University of Pittsburgh, Pittsburgh, PA), is a solid tumor of BALB/c (H-2d) origin, which grows aggressively in naive, syngeneic hosts following a s.c. transplant. Although the parental tumor cell line forms few metastatic foci in the lungs following i...
ORGANISM(S): Mus musculus 
2005-05-08 | E-MEXP-288 | biostudies-arrayexpress
TranscriptomicsMolecular characterization of tumor cells from the cerebrospinal fluid and matched primary tumors from metastatic breast cancer patients with leptomeningeal disease
We purified tumor cells in the CSF (M-bM-^@M-^\CSFTCM-bM-^@M-^]) from 15 metastatic breast cancer patients diagnosed with leptomeningeal disease using a two-step method involving immunomagnetic enrichment and fluorescence-activated cell sorting (IE/FACS). Magnetic beads coated with mAb to the epithe...
ORGANISM(S): Homo sapiens 
2014-01-09 | E-GEOD-46068 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of in vivo-derived CMS4-met cells and the in vitro-derived CMS4.sel cells using CMS4 cells as a reference sample
The CMS4 sarcoma, kindly provided by A. DeLeo (University of Pittsburgh, Pittsburgh, PA), is a solid tumor of BALB/c (H-2d) origin, which grows aggressively in naive, syngeneic hosts following a s.c. transplant. Although the parental tumor cell line forms few metastatic foci in the lungs following i...
ORGANISM(S): Mus musculus 
2005-05-08 | E-MEXP-286 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse sarcoma cell lines CMS4 vs. CMS4-met
To identify unique genes associated with tumor progression by comparing a poorly metastatic tumor cell line with a highly metastatic tumor cell line.
ORGANISM(S): Mus musculus 
2005-03-10 | E-MEXP-277 | biostudies-arrayexpress
MetabolomicsNeuronal Hyperactivity due to Loss of Inhibitory Tone in APOE4 Mice Lacking Alzheimer’s Disease-like Pathology
Metabolite profiling was performed on metabolites extracted from the entorhinal cortex and primary visual cortex of 14-15 month old APOE3/3, APOE3/4 and APOE4/4 mice. Metabolites were run on a TOF Mass Spectrometer using an ANP column. Initial analysis was done in an untargeted manner, and processin...
2017-09-05 | MTBLS530 | MetaboLights
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