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UnknownActive-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis.
Not available
S-EPMC6124814 | biostudies-literature
UnknownImmunogenic HSV-mediated oncolysis shapes the antitumor immune response and contributes to therapeutic efficacy.
Not available
S-EPMC3978812 | biostudies-literature
ProteomicsIdentification of SLFN5 as an intrinsic inhibitor of viral transcription antagonized by the herpes simplex virus ubiquitin ligase ICP0
Intrinsic antiviral host factors are proteins that can confer cellular defense by limiting virus replication. Viruses hijack ubiquitin machinery to modify the cellular proteome to subvert these host defenses. The herpes simplex virus 1 (HSV-1) expresses ICP0, which functions as an E3 ubiquitin ligas...
ORGANISM(S): Homo sapiens (Human) Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) Human alphaherpesvirus 1 
2020-09-14 | PXD018773 | Pride
Dicp0 Herpes simplex virus Slfn5 Ipond Hsv-1 Ubiquitin Icp0 
GenomicsSingle cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes
PRJNA520853 | ENA
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