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UnknownTumor-induced MDSC act via remote control to inhibit L-selectin-dependent adaptive immunity in lymph nodes.
Not available
S-EPMC5199197 | biostudies-literature
TranscriptomicsExpression data from unactivated vs. activated PBMCs (ion array)
Long-lasting activation of T cells requires up-regulation of many genes, for example of transcription factors, cytoskeletal proteins and cell surface proteins encluding ion channels. An increase of ion channel density at the cell surface reflects the needs to manage increased Ca2+ influx into the ...
ORGANISM(S): Homo sapiens 
2010-06-17 | E-GEOD-22387 | biostudies-arrayexpress
TranscriptomicsThe Transcriptome of Nrf2-Deficient Mice in Cigarette Smoke-Induced Emphysematous Changes
Cigarette smoke (CS) imposes a strong oxidative burden on exposed tissues resulting in a severely disturbed oxidant/antioxidant balance, which in the context of chronic exposure is assumed to be a key contributor to CS-related diseases. Because of its emerging central role in orchestrating the gener...
ORGANISM(S): Mus musculus 
2010-02-27 | E-GEOD-18344 | biostudies-arrayexpress
TranscriptomicsGene expression in neonatal NKT cells and lymphoma samples from mice with high E protein levels [Microarray Expression]
Inhibitor of DNA binding proteins (ID), including Id1-4, are transcriptional regulators involved in promoting cell proliferation and survival in various cell types. Although upregulation of Id proteins have been widely reported to be associated with a broad spectrum of tumors, recent studies have id...
ORGANISM(S): Mus musculus 
2017-04-20 | E-GEOD-73864 | biostudies-arrayexpress
UnknownExpression of relaxin-3 and its receptors in the hypothalamic-pituitary-ovary axis in layers and broiler breeders.
Not available
S-EPMC11981738 | biostudies-literature
UnknownMultilevel Risk Factors for Sleep-Disordered Breathing-Related Symptom Burden in an Urban Pediatric Community-Based Sample.
Not available
S-EPMC10786403 | biostudies-literature
TranscriptomicsSuv39h-dependent H3K9me3 represses intact retrotransposons in mouse embryonic stem cells
Heterochromatin is required to restrict aberrant expression of retrotransposons, but it remains poorly defined due to the underlying repeat-rich sequences. We dissected Suv39h-dependent histone H3 lysine 9 trimethylation (H3K9me3) by genome-wide ChIP-sequencing in mouse embryonic stem cells (ESCs). ...
ORGANISM(S): Mus musculus 
2014-06-26 | E-GEOD-57092 | biostudies-arrayexpress
GenomicsChIP-Seq of fly Schneider S2 cells to investigate CID islands
The centromere-specific Histone H3-variant CENH3 (also known as CENP-A) is considered to be an epigenetic mark for establishment and propagation of centromere identity. Pulse-induction of CENH3 (Drosophila CID) in Schneider S2 cells incorporates into noncentromeric regions and generates CID islands ...
ORGANISM(S): Drosophila melanogaster 
2011-07-15 | E-MTAB-652 | biostudies-arrayexpress
TranscriptomicsExpression data from ethanol and saline exposed mice [mRNA]
Mouse models of Fetal Alcohol Spectrum Disorder can be used to assess molecular changes underlying the disorder. Neonatal ethanol exposure in mice can be used to model third trimester ethanol exposure in humans. Mice were injected with 2.5 g/kg twice on each of postnatal days 4 and 7. Mice were allo...
ORGANISM(S): Mus musculus 
2015-03-07 | E-GEOD-66644 | biostudies-arrayexpress
UnknownMusic Restores Propriospinal Excitation During Stroke Locomotion.
Not available
S-EPMC7161673 | biostudies-literature
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