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TranscriptomicsThe role of Gaq in MLL leukemogenesis
Beta-catenin has a central role for self-renewal of leukemic stem cells in Mixed Lineage Leukemia (MLL)-arranged acute myeloid leukemia (AML), however its upstream modulators that can enhance this pathway remain largely unexplored. Through genome-wide gene expression analysis, we identified a previo...
ORGANISM(S): Mus musculus 
2016-02-25 | E-MTAB-4078 | biostudies-arrayexpress
TranscriptomicsExpression study between dental pulp cells from TRPC6-mut individual and control individuals
As TRPC6 channel induces CREB-mediated trancription, Dental pulp cells from TRPC6-mut patient and from 6 controls were analyzed in order to verify if the disruption of TRPC6 leads to transcriptional changes. Cells were grown until reach 80-90% of confluency in DMEM/F12 media supplemented with 15% fe...
ORGANISM(S): Homo sapiens 
2014-10-23 | E-GEOD-62620 | biostudies-arrayexpress
TranscriptomicsExpression study of human embryonic stem cells, dental pulp cells (DPCs) and induced pluripotent stem cells (iPSC) obtained from DPC for characterization of iPSC
iPSC were obtained from DPC from TRPC6-mut patient, a idiopathic autistic patient and a control. Original DPC and iPSC obtained were submited to expression analysis in order to check if the expression pattern obtained for the iPSC cells were closer related to embyonic cells than to the original DPC ...
ORGANISM(S): Homo sapiens 
2014-10-23 | E-GEOD-62622 | biostudies-arrayexpress
GenomicsGencode_550K
Lymphoma samples using HumanOmni
EGAD00010000949 | EGA
GenomicsGencode_15K
Lymphoma samples using CytoSNP
EGAD00010000947 | EGA
Genomicsena-DATASET-DKFZ-HIPO-22-04-2016-18:09:52:421-12 - samples
Paired-end RNA sequencing using total RNA from 136 primary lymphoma samples. Sequencing was performed on the Illumina HiSeq2000 with 300bp insert size. The dataset contains FASTQ files.
EGAD00001002056 | EGA
Genomicsena-DATASET-DKFZ-HIPO-22-04-2016-18:03:44:927-11 - samples
Whole exome sequencing from matched tumor-control samples of 121 primary lymphoma samples. Sequencing was performed on Illumina HiSeq2000. The dataset contains FASTQ files.
EGAD00001002055 | EGA
GenomicsGencode_500K
Lymphoma samples using 450k
EGAD00010000948 | EGA
GenomicsDrug-perturbation-based stratification of blood cancer
As new generations of targeted therapies emerge and tumor genome sequencing discovers increasingly comprehensive mutation repertoires, the functional relationships of mutations to tumor phenotypes remain largely unknown. Here, we measured ex vivo sensitivity of 246 blood cancers to 63 drugs alongsid...
EGAS00001001746 | EGA
UnknownPathway-Specific Polygenic Scores for Predicting Clinical Lithium Treatment Response in Patients With Bipolar Disorder.
Not available
S-EPMC12357302 | biostudies-literature
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