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MetabolomicsCo-exposure of di(2-ethylhexyl) phthalate (DEHP) decreased the submicron plastic stress in soil-plant system

The widespread use of agricultural plastic films has made micro- and nanoplastics (MNPs) and phthalate esters (PAEs) contaminants of emerging concern in agroecosystems. However, the interactive mechanisms underlying their combined pollution in soil-plant systems remain elusive. To fill this gap, ...

2025-08-22 | MTBLS12878 | MetaboLights
GenomicsMouse ES cells expressing catalytically inactive Ring1B display impaired Ring1B and H3K27me3 deposition.
ChIP-seq for H3K27me3 and Ring1B was performed in WT mESCs and mESCs containing catalytically inactive Ring1B (I53A mutant). Cells expressing catalytically inactive Ring1B maintain the spatial distribution of Ring1B and H3K27me3 but at reduced levels. These findings support the notion that PRC2 recr...
ORGANISM(S): Mus musculus 
2015-09-20 | E-GEOD-69955 | biostudies-arrayexpress
TranscriptomicsA master cistromic circuit governing hepatic fibrogenesis [expression array]
Liver fibrosis is a reversible wound-healing response to liver injury and hepatic stellate cells (HSCs) are central cellular players that mediate hepatic fibrogenesis. However, the molecular mechanisms that govern this process remain unclear. Expression profiling was used to explore the potential im...
ORGANISM(S): Rattus norvegicus 
2013-04-29 | E-GEOD-41579 | biostudies-arrayexpress
ProteomicsMS data on DBP-interacting proteins
Shotgun proteomic analyses of Flag-DBP or Flag-Luc (control) associated proteins
ORGANISM(S): Mus Musculus (mouse) 
2024-08-26 | PXD048376 | JPOST Repository
MetabolomicsSerum metabolomics analysis of patients with chronic obstructive pulmonary disease and 'frequent exacerbator' phenotype

BACKGROUND: Chronic obstructive pulmonary disease (COPD) exacerbations significantly contribute to morbidity and mortality. The complex nature of COPD presents challenges in accurately predicting and understanding frequent exacerbations.

OBJECTIVE: This stu...

2024-02-23 | MTBLS9119 | MetaboLights
TranscriptomicsWhole-genome gene expression profiles of non-tumorous human lung tissues: UBC set
We profiled genome-wide gene expression in non-tumorous human lung tissues. The overall goal of this project is to improve our molecular understanding of various lung diseases including lung cancer and chronic obstructive pulmonary disease (COPD). The samples from the University of British Columbia ...
ORGANISM(S): Homo sapiens 
2012-06-10 | E-GEOD-23529 | biostudies-arrayexpress
GenomicsPCGF Homologs and RYBP Define Functionally Distinct PRC1 Family Complexes
The heterogeneous nature of mammalian PRC1 complexes has hindered our understanding of their biological functions. Here, we present a comprehensive proteomic and genomic analysis that uncovered six major groups of PRC1 complexes each containing a distinct PCGF subunit, a RING1A/B ubiquitin ligase, a...
ORGANISM(S): Homo sapiens 
2012-02-09 | E-GEOD-34774 | biostudies-arrayexpress
TranscriptomicsExpression profiling of 40 NSCLC cell lines
INTRODUCTION: CDKN2A (p16) inactivation is common in lung cancer and occurs via homozygous deletions, methylation of promoter region, or point mutations. Although p16 promoter methylation has been linked to KRAS mutation and smoking, the associations between p16 inactivation mechanisms and other com...
ORGANISM(S): Homo sapiens 
2015-06-22 | E-GEOD-63882 | biostudies-arrayexpress
TranscriptomicsChIP-chip by tiling array of Drosophila Polycomb group protein Sce/Ring in larvae
Analysis of binding profile of the Polycomb group protein Sce/Ring in Drosophila melanogaster larvae.
ORGANISM(S): Drosophila melanogaster 
2011-04-03 | E-TABM-988 | biostudies-arrayexpress
UnknownHorizontal Gene Transfer of Genes Encoding Copper-Containing Membrane-Bound Monooxygenase (CuMMO) and Soluble Di-iron Monooxygenase (SDIMO) in Ethane- and Propane-Oxidizing Rhodococcus Bacteria.
Not available
S-EPMC8231442 | biostudies-literature
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