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GenomicsGenome-wide chromatin accessibility profile of human DIPG cell lines
Genome-wide chromatin accessibility profile of human DIPG cell lines
PRJNA1001514 | ENA
ProteomicsProteome of SUDIPG, SF7761 and primary non diseased brain samples
DIPG is a paediatric brainstem glioma with no cure. Cellular immunotherapy approaches require specific targeting of unique and tumour specific cell surface antigens, however, there is a paucity of known targets for DIPG. In this study we have used a proteomics approach to interrogate an array of pat...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD038372 | Pride
Brain Bruker Dipg Proteomics S-trap Dda 
GenomicsGenome-wide gene expression profile of human DIPG cell lines (ONC201 treatment)
Genome-wide gene expression profile of human DIPG cell lines (ONC201 treatment)
PRJNA1001515 | ENA
GenomicsChIP-seq of H3K27ac and H3K27me3 in HSJD-DIPG-007 cell line
Identification of super enhancer regions in the HSJD-DIPG-007 cell line and the associated genes with these regions. This study aims to evaluate the efficacy of combined use of BET and CBP inhibition in DIPG.
ORGANISM(S): Homo sapiens 
2020-08-01 | E-MTAB-8242 | biostudies-arrayexpress
TranscriptomicsChIP-seq of H3K27ac and H3K27me3 in HSJD-DIPG-007 cell line upon treatment with ICG-001 and JQ1
Identification of super enhancer regions in the HSJD-DIPG-007 cell line and the associated genes with these regions. This study aims to evaluate the efficacy of combined use of BET and CBP inhibition in DIPG.
ORGANISM(S): Homo sapiens 
2020-08-01 | E-MTAB-9152 | biostudies-arrayexpress
ProteomicsHuman diffuse intrinsic pontine glioma (DIPG) LC-MSMS
Diffuse intrinsic pontine glioma (DIPG), a lethal pediatric cancer driven by H3K27M oncohistones, exhibits aberrant epigenetic regulation and stem-like cell states. Here, we uncover an axis involving H3.3K27M oncohistones, CREB5/ID1, which sustains the stem-like state of DIPG cells, promoting malign...
ORGANISM(S): Homo sapiens (Human) 
2025-01-28 | PXD053094 | Pride
Human Dipg cell lines Ip-ms 
ProteomicsHuman diffuse intrinsic pontine glioma (DIPG) LC-MSMS
Diffuse intrinsic pontine glioma (DIPG), a lethal pediatric cancer driven by H3K27M oncohistones, exhibits aberrant epigenetic regulation and stem-like cell states. Here, we uncover an axis involving H3.3K27M oncohistones, CREB5/ID1, which sustains the stem-like state of DIPG cells, promoting malign...
ORGANISM(S): Homo sapiens (Human) 
2025-01-28 | PXD060271 | Pride
Human Dipg cell lines Ip-ms 
ProteomicsThe immunopeptidome and proteome of DIPG
DIPG is a devastating paediatric and young adult brainstem tumour with no cure and a median overall survival of 9 months. Cellular immunotherapy approaches require specific targeting of unique and tumour specific cell surface antigens, however, there is a paucity of known targets for DIPG. Here we u...
ORGANISM(S): Homo sapiens (Human) 
2023-09-25 | PXD038271 | Pride
Hla Proteomics Dipg Immunopeptidomics 
TranscriptomicsGenome-wide gene expression profile of human DIPG cell lines (ONC201 treatment)
To study the effect of ONC201 treatment on DIPG-VII, DIPG-IV, and DIPG-XIII cell lines, we treated cell lines and performed RNA-Seq analysis.
ORGANISM(S): Homo sapiens 
2023-12-31 | GSE239939 | GEO
GenomicsGenome-wide chromatin accessibility profile of human DIPG cell lines
To study the chromatin accessibility across the genome of DIPG-VII, DIPG-IV, and DIPG-XIII cell lines, we performed ATACseq (Assay for Transposase-Accessible Chromatin with high-throughput sequencing).
ORGANISM(S): Homo sapiens 
2023-12-31 | GSE239938 | GEO
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