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TranscriptomicsTranscription profiling of mouse dorsal root ganglia after diphtheria-toxin deletion of the Nav1.8-expressing cells using the cre/loxP system
Comparison of transcript levels after diphtheria-toxin deletion of the Nav1.8-expressing cells using the cre/loxP system.
Pain requires input from nociceptors which are specialised peripheral sensory neurons in dorsal root ganglia (DRG). To explore the nociceptor-specific mRNA profiles, we used ...
ORGANISM(S): Mus musculus 
2008-08-02 | E-MEXP-1622 | biostudies-arrayexpress
TranscriptomicsMicroarray of whole brain gene expression in transgenic adult female mice expressing primate diphtheria toxin receptor under Foxp3 promoter (Foxp3DTR) treated with either diphtheria toxin or vehicle
Peripheral regulatory T-cell (Treg) levels correlate with psychiatric outcomes in humans, and Treg-depletion induced by diptheria toxin administration in Foxp3DTR knock-in mice results in specific behaviour phenotypes. We examined the consequences of Treg depletion on whole brain gene expression i...
ORGANISM(S): Mus musculus 
2026-07-01 | E-MTAB-16677 | biostudies-arrayexpress
GenomicsModified Elek’s test improves in-vitro detection of diphtheria toxin
Modified Elek’s test improves in-vitro detection of diphtheria toxin
PRJEB108589 | ENA
ProteomicsProteomics of diphtheria toxoid vaccines reveals multiple proteins that are immunogenic and may contribute to protection of humans against Corynebacterium diphtheriae
Introduced for mass immunization in the 1920s, vaccines against diphtheria are among the oldest and safest vaccines known. The basic principle of their production is the inactivation of purified diphtheria toxin by formaldehyde cross-linking, which converts the potentially fatal toxin in a completel...
ORGANISM(S): Corynebacterium diphtheriae NCTC 13129 Clostridium tetani E88 
2019-04-18 | PXD012806 | Pride
Proteomics Mass spectrometry Coryebacteria Exoproteome Vaccination Secretome 
UnknownDetermination of Diphtheria Toxin in Bacterial Cultures by Enzyme Immunoassay.
Not available
S-EPMC9498204 | biostudies-literature
GenomicsEffects of Diphtheria Toxin and Compound 6p on HPKs (human primary keratinocytes)
Effects of Diphtheria Toxin and Compound 6p on HPKs (human primary keratinocytes)
PRJNA991972 | ENA
UnknownDetection of differences in the nucleotide and amino acid sequences of diphtheria toxin from Corynebacterium diphtheriae and Corynebacterium ulcerans causing extrapharyngeal infections.
Not available
S-EPMC254330 | biostudies-literature
UnknownHuman antibodies neutralizing diphtheria toxin in vitro and in vivo.
Not available
S-EPMC6969050 | biostudies-literature
UnknownDetection and Characterization of Diphtheria Toxin Gene-Bearing Corynebacterium Species through a New Real-Time PCR Assay.
Not available
S-EPMC7512153 | biostudies-literature
ProteomicsHelpful dirt: Why diphtheria toxoid vaccines may also protect against non-toxigenic Corynebacterium diphtheriae strains
Diphtheria toxoid vaccines are among the oldest and safest vaccines known. The basic principle of production is the inactivation of purified diphtheria toxin by formaldehyde cross-linking, which converts the potentially fatal toxin in a completely harmless protein aggregate, which is still immunogen...
ORGANISM(S): Corynebacterium diphtheriae NCTC 13129 Clostridium tetani E88 
2019-04-17 | PXD009289 | Pride
Proteomics Corynebacterium ulcerans Mass spectrometry Corynebacteria Exoproteome Vaccination Secretome 
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