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UnknownCleavage activates dispatched for Sonic Hedgehog ligand release.
Not available
S-EPMC5811216 | biostudies-literature
UnknownCryo-EM structure of the Hedgehog release protein Dispatched.
Not available
S-EPMC7159904 | biostudies-literature
UnknownRisk of Physical Injury for Dispatched Citizen Responders to Out-of-Hospital Cardiac Arrest.
Not available
S-EPMC8483463 | biostudies-literature
UnknownStructure of human Dispatched-1 provides insights into Hedgehog ligand biogenesis.
Not available
S-EPMC7362390 | biostudies-literature
UnknownDispatched uses Na+ flux to power release of lipid-modified Hedgehog.
Not available
S-EPMC8785653 | biostudies-literature
UnknownArchitecture of Dispatched, a Transmembrane Protein Responsible for Hedgehog Release.
Not available
S-EPMC8453165 | biostudies-literature
UnknownDispatched mediates Hedgehog basolateral release to form the long-range morphogenetic gradient in the Drosophila wing disk epithelium.
Not available
S-EPMC3150953 | biostudies-literature
UnknownDispatched and scube mediate the efficient secretion of the cholesterol-modified hedgehog ligand.
Not available
S-EPMC3682496 | biostudies-literature
ProteomicsScube2 primes Dispatched and ADAM10-mediated Shh release by recruiting HDL acceptors to the plasma membrane
Sonic hedgehog (Shh) morphogens are lipidated proteins that firmly attach to the outer plasma membrane (PM) of the cells that produce them. The process by which Shh is solubilized includes the transmembrane protein Dispatched1 (Disp), the soluble glycoprotein Scube2, the proteolytic removal of lipid...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD071371 | Pride
A disintegrin and metalloproteinase 10 Cholesterol Heparan sulfate Scube2 Dispatched Hedgehog High-density lipoprotein 
UnknownConserved cholesterol-related activities of Dispatched 1 drive Sonic hedgehog shedding from the cell membrane.
Not available
S-EPMC8403983 | biostudies-literature
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