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ProteomicsSpatially restricted proteomics reveals dynamic changes in the caveolin-1 interactome in response to increased membrane tension
Here, we used APEX2 proximity labelling technique coupled with mass spectrometry to define Cveolin-1 interactome at steady state and after hypo-osmotic shock. We created a stable cell line expressing Caveolin1-APEX2-EGFP in human retinal pigmented epithelial cells (RPE-1). Hypo osmotic shock was per...
ORGANISM(S): Homo sapiens (Human) 
2024-11-05 | PXD026464 | Pride
Caveolin-1  apex2  interactome  membrane tension 
TranscriptomicsMinocycline is an inhibitor of the TNF-alpha induced fusion of human M13SV1-Cre breast epithelial cells and human MDA-MB-435-pFDR1 breast cancer cells
Using a Cre-LoxP-based cell fusion assay we able to demonstrate that the fusion of human M13SV1-Cre breast epithelial cells and human MDA-MB-435-pFDR1 breast cancer cells was induced by TNF-alpha both under normoxic and hypoxic conditions. To investigate the impact of TNF-alpha on the gene expressio...
ORGANISM(S): Homo sapiens 
2018-04-23 | E-MTAB-6084 | biostudies-arrayexpress
UnknownAlteration in the gene expression pattern of primary monocytes after adhesion to endothelial cells.
Not available
S-EPMC1838499 | biostudies-literature
UnknownTranscriptional cooperation of PBX1 and PAX6 in adult neural progenitor cells.
Not available
S-EPMC8545929 | biostudies-literature
UnknownFunctional Significance of Conserved Cysteines in the Extracellular Loops of the ATP Binding Cassette Transporter Pdr11p.
Not available
S-EPMC7822014 | biostudies-literature
ProteomicsSuccession of proteomic, transcriptomic and exometabolomic signatures in Alteromonas macleodii degrading a mix of macroalgal polysaccharides
Polysaccharides from macroalgae are important bacterial nutrient source and central biogeochemical component in the oceans. To illuminate the cellular mechanisms of polysaccharide degradation by marine bacteria, growth of Alteromonas macleodii 83-1 on a mix of laminarin, alginate and pectin was char...
ORGANISM(S): Alteromonas macleodii 
2018-08-22 | PXD008280 | Pride
Catabolite repression Polysaccharide degradation Alteromonas 
UnknownNS5-targeting nucleoside analogs inhibit dengue virus and other flaviviruses.
Not available
S-EPMC12928577 | biostudies-literature
ProteomicsMassSpecPreppy - an end-to-end solution for automated protein concentration determination and flexible sample digestion for proteomics applications
In proteomics, fast, efficient and highly reproducible sample preparation are of utmost importance, particularly in view of fast scanning mass spectrometers enabling analyses of large sample series. To address this need, we have developed the web application MassSpecPreppy that operates on the open ...
ORGANISM(S): Saccharomyces Cerevisiae Strain C13-aby.s86 Escherichia Coli K-12 (ncbitaxon:83333) Homo Sapiens (ncbitaxon:9606) 
2023-07-20 | MSV000092489 | MassIVE
UnknownInfluence of wood species on toxicity of log-wood stove combustion aerosols: a parallel animal and air-liquid interface cell exposure study on spruce and pine smoke.
Not available
S-EPMC7296712 | biostudies-literature
UnknownDemonstration of reduced neoclassical energy transport in Wendelstein 7-X.
Not available
S-EPMC8357633 | biostudies-literature
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