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This study has determined structure of transcription initiation complexes including a DNA-bound activator, RNA polymerase II (Pol II), and Mediator on a divergent promoter GAL80/SUT719 using a combination of cryo-EM and XL-MS analyses. Our cryo-EM single-particle analysis reveals a dimeric form of ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-05-22 | PXD036149 | Pride
Here we describe a novel class of short RNAs that indicate widespread divergent transcription at mammalian promoters Small RNA cloning and deep sequencing from human embryonic stem cells, derived neural progenitors and neurons
ORGANISM(S): Homo sapiens 
Here we describe a novel class of short RNAs and high-resolution ChIP-Seq data that together indicate widespread divergent transcription at mammalian promoters and suggest the existence of novel regulatory mechanisms concerning both initiation and elongation by RNA polymerase II. ChIP-seq in murine ...
ORGANISM(S): Mus musculus 
Combinatorial actions of relatively few transcription factors control hematopoietic differentiation. To investigate this process in erythro-megakaryopoiesis, we correlated the genome-wide chromatin occupancy signatures of four master hematopoietic transcription factors (GATA1, GATA2, TAL1, and FLI1)...
ORGANISM(S): Mus musculus 
Combinatorial actions of relatively few transcription factors control hematopoietic differentiation. To investigate this process in erythro-megakaryopoiesis, we correlated the genome-wide chromatin occupancy signatures of four master hematopoietic transcription factors (GATA1, GATA2, SCL/TAL1 and FL...
ORGANISM(S): Mus musculus 
Divergent transcription from lentiviral gene editing of cancer cells
Hda1C restricts burst frequency to limit divergent non-coding transcription
CTCF blocks anti-sense transcription initiation at divergent gene promoters [PRO-Seq]
CTCF blocks anti-sense transcription initiation at divergent gene promoters [ChIP-Seq]
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