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TranscriptomicsRole of DksA in nitrosative stress
Transcriptional profiles of wt and dksA minus Salmonella enterica sv Typhimurium 14028S in E salts minimal medium in response to 5 mM DETANONOate for 30 min Total RNA was harvested from three biological replicates of wt and dksA mutant cultures exposed or unexposed to 5mM DETANONOate for 30min in E ...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 
2014-03-31 | E-GEOD-33529 | biostudies-arrayexpress
TranscriptomicsDksA Guards Elongating RNA Polymerase Against Ribosome-Stalling-Induced Arrest
In bacteria, translation-transcription coupling inhibits RNA polymerase (RNAP) stalling. We present evidence suggesting that, upon amino acid starvation, inactive ribosomes promote rather than inhibit RNAP stalling. We developed an algorithm to evaluate genome-wide polymerase progression independent...
ORGANISM(S): Escherichia coli 
2014-04-21 | E-GEOD-54669 | biostudies-arrayexpress
TranscriptomicsExpression data from E. coli cells overexpressing either GreA or GreB in ppGpp0 cells in the dksA+ or dksA- background
Strains devoid of ppGpp (ΔrelA ΔspoT; called ppGpp0), and ppGpp0 dksA- exhibit several amino acid requirements for growth on minimal media. We found that overexpression of DksA can complement some of those requirements. Since DksA is a factor that binds to the RNA polymerase secondary channel, we wo...
ORGANISM(S): Escherichia coli 
2011-10-26 | E-GEOD-28795 | biostudies-arrayexpress
TranscriptomicsRole of DksA in the pathogenesis and physiology of Campylobacter jejuni.
DksA is well-known for its regulatory role in the transcription of ribosomal RNA and genes involved in amino acid synthesis in many bacteria. DksA is also reported to control expression of virulence genes in pathogenic bacteria. Here, we elucidated the roles of the DksA-like protein (CJJ81176_0160, ...
ORGANISM(S): Campylobacter jejuni subsp. jejuni 81-176 
2008-05-05 | E-GEOD-9866 | biostudies-arrayexpress
ProteomicsVibrio cholerae (p)ppGpp and DksA mutants SWATH
This study elucidates the whole proteome changes in the wild type and gnetically modified strains of Vibrio cholerae. Label-free SWATH-MS is used for protein quantitation following genetic modifications in alarmone (p)ppGpp metabolizing genes and transcription factor DksA.
ORGANISM(S): Vibrio cholerae O1 str. Haiti 
2025-01-29 | PXD055059 | Pride
Lc-msms Vibrio cholerae Dksa Swath-ms (p)ppgpp 
GenomicsDksA controls the response of the Lyme disease spirochete Borrelia burgdorferi to starvation
DksA controls the response of the Lyme disease spirochete Borrelia burgdorferi to starvation
PRJNA487786 | ENA
GenomicsDksA acts as a transcriptional switch in stress and virulence in Acinetobacter baumannii
DksA acts as a transcriptional switch in stress and virulence in Acinetobacter baumannii
PRJNA715173 | ENA
TranscriptomicsExpression data from E. coli cells overexpressing either GreA or GreB in ppGpp0 cells in the dksA+ or dksA- background
Strains devoid of ppGpp (ΔrelA ΔspoT; called ppGpp0), and ppGpp0 dksA- exhibit several amino acid requirements for growth on minimal media. We found that overexpression of DksA can complement some of those requirements. Since DksA is a factor that binds to the RNA polymerase secondary channel, we wo...
ORGANISM(S): Escherichia coli 
2011-10-27 | GSE28795 | GEO
GenomicsUnderstanding the roles of dksA and greA in inorganic polyphosphate accumulation in Escherichia coli
Understanding the roles of dksA and greA in inorganic polyphosphate accumulation in Escherichia coli
PRJNA604995 | ENA
TranscriptomicsRole of DksA in the pathogenesis and physiology of Campylobacter jejuni.
DksA is well-known for its regulatory role in the transcription of ribosomal RNA and genes involved in amino acid synthesis in many bacteria. DksA is also reported to control expression of virulence genes in pathogenic bacteria. Here, we elucidated the roles of the DksA-like protein (CJJ81176_0160, ...
ORGANISM(S): Campylobacter jejuni Campylobacter jejuni subsp. jejuni 81-176 
2008-05-06 | GSE9866 | GEO
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