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ProteomicsHuman N-terminal proteome using TMPP labelling and dN-TOP approach
The present study describes the free N-terminome analysis of human mitochondria-enriched samples using trimethoxyphenylphosphonium (TMPP) labelling approaches and dN-TOP validation of the proteomics data acquired with an Orbitrap mass spectrometer. The doublet N-terminal oriented proteomics (dN-TOP)...
ORGANISM(S): Homo sapiens (Human) 
2026-03-23 | PXD064426 | Pride
Dn-top approach Free n-terminome analysis Human mitochondria 
ProteomicsA combined N-terminomics and shotgun proteomics approach to investigate the responses of human cells to rapamycin and zinc at the mitochondrial level
This study aims investigating the impact of rapamycin and zinc at subtoxic doses on the human mitochondrial proteome. Experiments were performed on U397 monocytic cells. A dN-TOP strategy, combining shotgun proteomics and N-terminomics, was applied to study both internal and N-terminal peptides of t...
ORGANISM(S): Homo sapiens (Human) 
2019-05-14 | PXD010572 | Pride
N-terminome analysis Mitochondria Nanolc-ms/ms Dn-top strategy Differential analysis 
ProteomicsHuman “free-N-terminome” analysis
The high throughput characterization of protein N-termini is becoming an emerging challenge in the proteomics and proteogenomics fields. The present study describes the N-terminal oriented analysis of human mitochondria enriched samples by the trimethoxyphenyl phosphonium (TMPP) labeling approach (N...
ORGANISM(S): Homo sapiens (Human) 
2015-06-02 | PXD001522 | Pride
Human mitochondria Free n-terminome analysis Dn-top approach Proteogenomics 
ProteomicsHuman “free-N-terminome” analysis
The high throughput characterization of protein N-termini is becoming an emerging challenge in the proteomics and proteogenomics fields. The present study describes the N-terminal oriented analysis of human mitochondria enriched samples by the trimethoxyphenyl phosphonium (TMPP) labeling approach (N...
ORGANISM(S): Homo sapiens (Human) 
2015-06-02 | PXD001523 | Pride
Human mitochondria Free n-terminome analysis Dn-top approach Proteogenomics 
ProteomicsHuman “free-N-terminome” analysis
The high throughput characterization of protein N-termini is becoming an emerging challenge in the proteomics and proteogenomics fields. The present study describes the N-terminal oriented analysis of human mitochondria enriched samples by the trimethoxyphenyl phosphonium (TMPP) labeling approach (N...
ORGANISM(S): Homo sapiens (Human) 
2015-06-02 | PXD001521 | Pride
Human mitochondria Free n-terminome analysis Dn-top approach Proteogenomics 
ProteomicsA combined N-terminomics and shotgun proteomics approach to investigate the responses of human cells to rapamycin and zinc at the mitochondrial level
This study aims at investigating the impact of rapamycin and zinc at subtoxic doses on the human mitochondrial proteome. Experiments were performed on U397 monocytic cells. A dN-TOP strategy, combining shotgun proteomics and N-terminomics, was applied to study both internal and N-terminal peptides o...
ORGANISM(S): Homo sapiens (Human) 
2019-05-14 | PXD010220 | Pride
N-terminome analysis Mitochondria Nanolc-ms/ms Dn-top strategy Differential analysis 
ProteomicsHuman “free-N-terminome” analysis
The high throughput characterization of protein N-termini is becoming an emerging challenge in the proteomics and proteogenomics fields. The present study describes the N-terminal oriented analysis of human mitochondria enriched samples by the trimethoxyphenyl phosphonium (TMPP) labeling approach (N...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000080204 | MassIVE
UnknownTargeting Wnt/β-Catenin Activated Cells with Dominant-Negative N-cadherin to Reduce Neointima Formation.
Not available
S-EPMC5430493 | biostudies-literature
UnknownA Gene-Based Positive Selection Detection Approach to Identify Vaccine Candidates Using Toxoplasma gondii as a Test Case Protozoan Pathogen.
Not available
S-EPMC6109633 | biostudies-literature
UnknownUncovering the Mechanism of Astragalus membranaceus in the Treatment of Diabetic Nephropathy Based on Network Pharmacology.
Not available
S-EPMC7079250 | biostudies-literature
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