Dna methyltransferases

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Unknown (1555)
Genomics (884)
Transcriptomics (498)
Methylation profiling (179)
Proteomics (54)
Other (32)
Metabolomics (5)
Multiomics (1)

Organisms

Mus musculus (404)
Homo sapiens (311)
Arabidopsis thaliana (96)
Drosophila melanogaster (32)
Saccharomyces cerevisiae (25)
Rattus norvegicus (15)
Caenorhabditis elegans (8)
Schizosaccharomyces pombe (6)
Escherichia coli (6)
Vibrio cholerae (4)
synthetic construct (4)
Camponotus floridanus (3)
Harpegnathos saltator (3)
Glycine max (3)
Aspergillus flavus (3)
Tetrahymena thermophila (3)
Schmidtea mediterranea (2)
Oryza sativa Indica Group (2)
Bos taurus (2)
Gallus gallus (2)
Helicobacter pylori P12 (2)
Brassica carinata x Brassica rapa (1)
Geobacter metallireducens (1)
Schistocerca gregaria (1)
Bradyrhizobium japonicum (1)
Escherichia coli O157:H7 (1)
Methanosarcina mazei (1)
Schistosoma mansoni (1)
Mycobacterium tuberculosis (1)
Pseudomonas aeruginosa PAO1 (1)

Organisms

Mus musculus (226)
Homo sapiens (162)
Arabidopsis thaliana (63)
Saccharomyces cerevisiae (14)
Drosophila melanogaster (8)
Rattus norvegicus (5)
Botrytis cinerea B05.10 (3)
Adineta vaga (3)
Schizosaccharomyces pombe (3)
Danio rerio (3)
Helicobacter pylori P12 (2)
Petromyzon marinus (2)
Streptococcus mutans UA159 (2)
Komagataella phaffii (2)
Synechocystis sp. PCC 6803 (2)
Neurospora crassa (2)
Phaeodactylum tricornutum (2)
Vibrio cholerae (2)
Caenorhabditis elegans (2)
Helicobacter pylori (2)
Pseudomonas aeruginosa (2)
synthetic construct (2)
Borreliella mayonii (1)
Paramecium bursaria Chlorella virus 1 (1)
Cryphonectria parasitica (1)
Plasmodium falciparum 3D7 (1)
Geobacillus kaustophilus (1)
Tribolium castaneum (1)
Aspergillus flavus (1)
Helicobacter pylori 26695 (1)

Repository

ENA (624)
geo (527)
biostudies-arrayexpress (437)
pride (34)
PeptideAtlas (8)
MassIVE (7)
EGA (6)
MetaboLights (5)
jPOST (3)
PanoramaPublic (1)

Tissue

Others (8)
Cell culture (7)
Embryonic stem cell (7)
Epithelial cell (4)
Brain (2)
Permanent cell line cell (2)
Blood cell (1)
Cell suspension culture (1)
Embryo (1)
Epithelial cell of cervix (1)
Liver (1)
Lung (1)
Root (1)
Shoot (1)
Single nucleate cell (1)
Stomach (1)
Whole body (1)

Disease

Disease free (3)
Hepatocellular carcinoma (2)
Acute leukemia (1)
Colon cancer (1)
Plasmodium falciparum malaria (1)

Technology Type

Mass Spectrometry (34)
Shotgun proteomics (18)
Affinity purification coupled with mass spectrometry proteomics (10)
Bottom-up proteomics (5)
Mass spectrometry (3)
SWATH MS (3)
Illumina HiSeq 2000 (2)
Mass spectrometry assay (2)
Data-dependent acquisition (2)
NextSeq 500, ILLUMINA, Illumina HiSeq 2500 (1)
Gel-based experiment (1)
SRM/MRM (1)
Top-down proteomics (1)

Instrument Platform

Illumina HiSeq 2500 (8)
Illumina MiSeq (6)
NextSeq 2000 (5)
NextSeq 500 (4)
Illumina HiSeq 2000 (3)
Q Exactive (3)
PromethION (2)
Windows 7 (2)
DNBSEQ-G400 (2)
NextSeq 550 (2)
Orbitrap Exploris 240 (2)
Liquid Chromatography MS - alternating - hilic (2)
Element AVITI (1)
Illumina BeadArray reader (1)
Illumina Genome Analyzer IIx (1)
G2565BA DNA microarray scanner [Agilent] (1)
ScanArray Express HT [PerkinElmer] (1)
Axon GenePix 4000B scanning hardware (1)
Flow cytometer (1)
Flow Cytometer (1)
Illumina NovaSeq X (1)
GridION (1)
MinION (1)
Illumina HiSeq 1500 (1)
Illumina NovaSeq 6000 (1)
Illumina HiSeq 4000 (1)
Orbitrap Fusion ETD (1)
Q Exactive HF-X (1)
Diode array detection MS - alternating - reverse phase (1)
Liquid Chromatography MS - positive (1)

Publication Date

2013 (108)
2014 (99)
2015 (79)
2016 (74)
2024 (56)
2022 (55)
2011 (53)
2012 (52)
2023 (51)
2019 (51)
2017 (50)
2025 (47)
2021 (46)
2026 (45)
2020 (40)
2010 (38)
2018 (30)
2008 (21)
2009 (17)
2007 (5)
2005 (2)
2004 (1)
2006 (1)

UNIPROT ID/AC

A0A024R563 (8)
A0A024RC46 (8)
A0A087WXI0 (8)
A0A0A0MR66 (8)
A0A0A0MSA7 (8)
A0A0B4J220 (8)
A0A0C4DG89 (8)
A0AVT1 (8)
A1L390 (8)
A3KMH1 (8)
A5A3E0 (8)
A6NHL2 (8)
A6NHQ2 (8)
A6NHR9 (8)
A6NMQ1 (8)
A6NNZ2 (8)
A8MTJ3 (8)
A9CQZ4 (8)
A9IYQ1 (8)
B1AK88 (8)
B2RPK0 (8)
B2RXF3 (8)
B3KML9 (8)
B3KT93 (8)
B3KW93 (8)
B4DHB3 (8)
B4DKM5 (8)
B4DL86 (8)
B4DPR2 (8)
B4DRV9 (8)

ENSEMBL ID

ENSG00000170477 (8)
ENSG00000247315 (6)

CHEBI ID

CHEBI:16255 (3)
CHEBI:16680 (3)
CHEBI:18132 (3)
CHEBI:16708 (3)
CHEBI:16610 (3)
CHEBI:37024 (3)
CHEBI:17509 (3)
CHEBI:24267 (2)
CHEBI:28862 (2)
CHEBI:34496 (2)
CHEBI:27469 (2)
CHEBI:17768 (2)
CHEBI:24809 (2)
CHEBI:5417 (2)
CHEBI:17431 (2)
CHEBI:18009 (2)
CHEBI:21553 (2)
CHEBI:17057 (2)
CHEBI:17992 (2)
CHEBI:28281 (2)
CHEBI:20794 (2)
CHEBI:44510 (2)
CHEBI:17672 (2)
CHEBI:16192 (2)
CHEBI:35825 (2)
CHEBI:15584 (2)
CHEBI:18066 (2)
CHEBI:17713 (2)
CHEBI:17200 (2)
CHEBI:17553 (2)

Metabolite Name

Carbamoyl phosphate (2)
7-methylguanosine (2)
Tridecanedioic acid (2)
Indole-3-carboxylic acid (2)
Cholic acid (2)
Spermidine (2)
N-Acetylputrescine (2)
Tetradecanedioic acid (2)
Hexadecanedioic acid (2)
1-Methyladenosine (2)
Tripterin (1)
D-myo-Inositol-1,3,4-triphosphate (1)
8-iso-15-keto Prostaglandin F2alpha (1)
1-amino-1-cyclobutane carboxylic acid (1)
1-aminopentadecane (1)
3-phenylbutyric acid (1)
Val-Pro-Ala (1)
Alpha-D-Glucopyranoside, beta-D-fructofuranosyl (1)
Etiocholanone (1)
LPC(O-16:1/0:0) (1)
LPE(15:0/0:0) (1)
LPC(O-18:1/0:0) (1)
N-Methyl-alpha-aminoisobutyric acid (1)
Coenzyme II (beta-NADP) (1)
Carnitine 2-methyl-C4 (1)
N-Alpha-acetyl-L-lysine (1)
N-Acetyl-5-Hydroxytryptamine (1)
(S)-2-Hydroxy-3-phenylpropanoic acid (1)
(R)-3-Hydroxymyristic acid (1)
D-(+)-talose (1)

First Public Date

2024 (69)
2014 (65)
2025 (53)
2022 (51)
2023 (47)
2020 (46)
2017 (46)
2019 (45)
2021 (44)
2026 (37)
2018 (37)
2013 (31)
2015 (28)
2016 (25)

Classification

bacteria (13)
helminths (1)
fungi (1)
viruses (1)
protozoa (1)

Modification

N6 (2)
N6-dimethyl-L-lysine (1)

Study type

Transcription profiling by array (133)
ChIP-seq (80)
RNA-seq of coding RNA (69)
Methylation profiling by high throughput sequencing (68)
Methylation profiling by array (20)
ChIP-chip by tiling array (13)
Other (13)
RNA-seq of non coding RNA (11)
Transcription profiling by tiling array (5)
Bisulfite-seq (5)
DNA-seq (5)
Cell line - High-throughput sequencing (3)
ChIP-chip by array (2)
Unknown experiment type (1)
Animal - One-color microarray (1)
Plant - High-throughput sequencing (1)
RNAi profiling by array (1)
Genotyping by array (1)
Comparative genomic hybridization by array (1)
ATAC-seq (1)
Ribo-seq (1)
Genotyping by high throughput sequencing (1)
RNA-seq of coding RNA from single cells (1)

Release Date

2022 (146)
2021 (146)
2013 (142)
2015 (133)
2014 (133)
2020 (122)
2023 (121)
2016 (115)
2025 (111)
2019 (111)
2017 (106)
2012 (104)
2018 (92)
2011 (86)
2010 (76)
2024 (71)
2008 (41)
2009 (36)
2026 (20)
2007 (15)
2006 (13)
2005 (11)
2003 (9)
2002 (9)
2001 (9)
2000 (5)
1999 (5)
2004 (3)
1998 (1)

Lab affiliation

Lab. Neuro-oncologie en klinische en kanker proteomics Department of Neurology Erasmus MC (2)
Proteomics program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark (2)
1. Department of Integrative Plant Biology, Institute of Plant Genetics, Polish Academy of Sciences, Poznań, Poland. 2. Associação CECOLAB, Rua Nossa Sra. da Conceição2, 3405-155 Oliveira do Hospital, Portugal (1)
Albert Einstein College of Medicine (1)
Biological Engineering, CEHS, MIT (1)
Cancer Epigenetics Group, Josep Carreras Leukaemia Research Institute, 08916, Badalona, Barcelona, Catalonia, Spain. (1)
Cancer Epigenetics Group, Josep Carreras Leukaemia Research Institute, 08916, Badalona, Barcelona, Catalonia, Spain (1)
Cell Biology and Epigenetics, Department of Biology, Technical University of Darmstadt, Darmstadt, Germany (1)
Centre Armand-Frappier Santé Biotechnologie, Institut National de la Recherche Scientifique (INRS), Laval, QC, Canada (1)
Centre for Epigenetics and Department of Biochemistry and Molecular Biology, University of Southern Denmark Campusvej 55 DK-5230 Odense M, Denmark (1)
Chair of chromatin replication and architecture, Institute of Cell Biology, University of Edinburgh, School of Biological Sciences Kings Buildings Roger Land Building, room 1.63 Alexander Crum Brown Road Edinburgh EH9 3FF, UK (1)
Department of Biological Sciences, University of Maryland Baltimore County, Baltimore, MD 21230 (1)
Department of Biology II and Center for Integrated Protein Science Munich (CIPSM), Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany (1)
Department of Chemistry and Biochemistry, University of California San Diego (1)
Department of Convergence Medicine, Convergence Medicine Research Center/Biomedical Research Center, Asan Medical Center, Asan Institute for Life Sciences, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea. (1)
Department of Internal Medicine, Morsani College of Medicine, University of South Florida (1)
Department of Molecular Medicine, Medical School, University of Padua, Padua 35121, Italy (1)
Department of Plant Science and Technology, Chung-Ang University, Anseong, Republic of Korea (1)
Institute for Chemical Epigenetics Department of Chemistry LMU München Würmtalstr. 201 81375 Munich Germany (1)
Institute for Glycomics, Griffith University (1)
Institute for Glycomics, Griffith University, Gold Coast, Queensland 4215, Australia (1)
Institute for Glycomics, Griffith University, Gold Coast, Queensland, 4222, Australia (1)
Institute of Chemistry, Academia Sinica (1)
Institute of Functional Epigenetics, Helmholtz Zentrum München, Deutsches Forschungszentrum fuer Gesundheit und Umwelt (GmbH) Ingolstaedter Landstr. 1, 85764, Neuherberg, Germany (1)
LMU Muenchen (1)
MRC-LMS: Head of Proteomics and Metabolomics Core Facility (1)
Molecular Cell and Developmental Biology, School of Life Sciences, University of Dundee, United Kingdom (1)
Proteomics & Metabolomics Facility MRC London Institute of Medical Sciences Hammersmith Hospital Campus Du Cane Road London, W12 0NN United Kingdom (1)
Shandong University (1)
Systems Biology Initiative, School of Biotechnology and Biomolecular Sciences, University of New South Wales, New South Wales, 2052, Australia (1)

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Virus-encoded glycosyltransferases hypermodify DNA with diverse glycans

Enzymatic modification of DNA nucleobases can coordinate gene expression, nuclease protection or mutagenesis. We recently discovered a clade of phage-specific cytosine methyltransferase (MT) and 5-methylpyrimidine dioxygenase (5mYOX) enzymes that produce 5-hydroxymethylcytosine (5hmC) as a precur...

2024-08-22 | MTBLS10724 | MetaboLights

Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation

DNA methylation is an epigenetic modification associated with transcriptional repression of promoters and is essential for mammalian development. Establishment of DNA methylation is mediated by the de novo DNA methyltransferases DNMT3A and DNMT3B, whereas DNMT1 ensures maintenance of methylation thr...

ORGANISM(S): Mus musculus

2015-01-20 | E-GEOD-57411 | biostudies-arrayexpress

Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation

This SuperSeries is composed of the SubSeries listed below. DNA methylation is an epigenetic modification associated with transcriptional repression of promoters and is essential for mammalian development. Establishment of DNA methylation is mediated by the de novo DNA methyltransferases DNMT3A and...

ORGANISM(S): Mus musculus

2015-01-22 | E-GEOD-57413 | biostudies-arrayexpress

Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation

ORGANISM(S): Mus musculus

2015-01-20 | E-GEOD-57412 | biostudies-arrayexpress

DDM1 and RdDM are the major regulators of transposon DNA methylation in Arabidopsis

Eukaryotic DNA methylation is found in silent transposable elements and active genes. Nucleosome remodelers of the DDM1/Lsh family are thought to be specifically required to maintain transposon methylation, but the reason for this is unknown. Here, we find that a chromatin gradient that extends from...

ORGANISM(S): Arabidopsis thaliana

2013-04-17 | E-GEOD-41302 | biostudies-arrayexpress

DNA methyltransferases are required to induce heterochromatic re-replication in Arabidopsis.

The relationship between epigenetic marks on chromatin and the regulation of DNA replication is poorly understood. Mutation of the H3K27 methyltransferase genes, ARABIDOPSIS TRITHORAX-RELATED PROTEIN5 (ATXR5) and ATXR6, result in re-replication (repeated origin firing within the same cell cycle). He...

ORGANISM(S): Arabidopsis thaliana

2012-08-07 | E-GEOD-38286 | biostudies-arrayexpress

Maintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (Dnmt3ab KO ChIP-Seq)

During mammalian development DNA methylation patterns need to be reset in primordial germ cells (PGC) and preimplantation embryos. However, many retro-transposons and imprinted genes are resistant to such global epigenetic reprogramming via hitherto undefined mechanisms. Here, we report that some of...

ORGANISM(S): Mus musculus

2014-06-03 | E-GEOD-47878 | biostudies-arrayexpress

Maintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (Dnmt3ab KO RNA-Seq)

ORGANISM(S): Mus musculus

2014-06-03 | E-GEOD-47883 | biostudies-arrayexpress

DNA methyltransferases are complementary in maintaining DNA methylation in embryonic stem cells

PRJNA860964 | ENA

Maintenance of DNA methylation in embryonic stem cells depends on the histone H3K9 methyltransferases (Dnmt3ab KO Methyl-Seq)

ORGANISM(S): Mus musculus

2014-06-03 | E-GEOD-47893 | biostudies-arrayexpress