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GenomicsTranscriptomics DNAJC15 and DNAJC19 knockdown in HeLa cells
Transcriptomics DNAJC15 and DNAJC19 knockdown in HeLa cells
PRJNA1274417 | ENA
UnknownTargeting DNAJC19 overcomes tumor growth and lung metastasis in NSCLC by regulating PI3K/AKT signaling.
Not available
S-EPMC8254338 | biostudies-literature
UnknownNovel homozygous pathogenic mitochondrial DNAJC19 variant in a patient with dilated cardiomyopathy and global developmental delay.
Not available
S-EPMC9356550 | biostudies-literature
UnknownMutations in DNAJC19 cause altered mitochondrial structure and increased mitochondrial respiration in human iPSC-derived cardiomyocytes.
Not available
S-EPMC10792641 | biostudies-literature
UnknownPreviously Unreported Biallelic Mutation in DNAJC19: Are Sensorineural Hearing Loss and Basal Ganglia Lesions Additional Features of Dilated Cardiomyopathy and Ataxia (DCMA) Syndrome?
Not available
S-EPMC5585102 | biostudies-literature
ProteomicsSILAC-based subcellular fractionation (PM,Golgi,soluble) upon DNAJC15 and DNAJC19 knockdown in HeLa cells
Mitochondria adapt to cellular stress to ensure cell survival. The stress-regulated mitochondrial peptidase OMA1 orchestrates these adaptive responses, which limit mitochondrial fusion and promote mitochondrial stress signaling and metabolic rewiring. Here, we show that cellular stress adaptation in...
ORGANISM(S): Homo sapiens (Human) 
2025-12-16 | PXD061185 | Pride
Dnajc19 Hela Silac Dnajc15 Subcellular 
TranscriptomicsTranscriptomics DNAJC15 and DNAJC19 knockdown in HeLa cells
To better understand how OMA1 affects mitochondrial proteostasis and stress responses, we performed a proteomic survey of OMA1-deficient cells for proteolytic substrates. We demonstrate that OMA1 cleaves the mitochondrial chaperone DNAJC15 facilitating its degradation by the mitochondrial m-AAA prot...
ORGANISM(S): Homo sapiens 
2025-12-19 | GSE299431 | GEO
UnknownRole of Magmas in protein transport and human mitochondria biogenesis.
Not available
S-EPMC2838536 | biostudies-literature
UnknownFunctional Diversity of Human Mitochondrial J-proteins Is Independent of Their Association with the Inner Membrane Presequence Translocase.
Not available
S-EPMC5016132 | biostudies-literature
UnknownGenital Abnormalities and Growth Retardation as Early Signs of Dilated Cardiomyopathy with Ataxia Syndrome.
Not available
S-EPMC10821800 | biostudies-literature
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