Sort   by:  
 Page size 
One of the greatest obstacles to eliminating TB is the lack of predictive and diagnostic biomarkers. Exosomes are a promising alternative source of biomarkers for TB since they can carry mycobacterial antigens. We hypothesize that exosomes from Mtb-infected macrophages exhibit a characteristic selec...
ORGANISM(S): Homo sapiens (Human) 
2016-12-20 | PXD004062 | Pride
The scope of this project is to investigate dynamic and persistent proteomic changes in tuberculosis (TB) patients during the course of treatment by analyzing paired bronchial alveolar lavage fluid (BALf) and serum samples collected at diagnosis and after 25 weeks of therapy. By comparing patient sa...
ORGANISM(S): Mycobacterium tuberculosis H37Rv Homo sapiens (Human) 
2026-03-17 | PXD073337 | Pride
Tuberculosis (TB) is the deadliest infectious disease worldwide. One obstacle hindering the elimination of TB is our lack of understanding of host-pathogen interactions. Exosomes, naturally loaded with microbial molecules, are circulating markers of TB. Changes in the host protein composition of exo...
ORGANISM(S): Homo sapiens (Human) 
2018-08-06 | PXD010659 | Pride
Identification of cellular proteins mediating presentation of bacterial antigens by the MHC I-related protein MR1. MR1 mutant proteins that differ in their capacity to present antigens from different sources were immunoprecipitated and their interacting proteins were compared to identify candidate p...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD062277 | Pride
Sort   by:  
 Page size