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Mutations in the adiponectin receptor 1 gene (AdipoR1) lead to retinitis pigmentosa and are associated with age-related macular degeneration (AMD). This study explores the effects of AdipoR1 gene deficiency in mice, revealing a striking decline in ω3 polyunsaturated fatty acids (PUFA), an increase i...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-23 | PXD050916 | Pride
To obtain an unbiased, thorough understanding of the biological pathways implicated in atRAL-induced cytotoxicity and PDE inhibitor-mediated cytoprotection, we performed a mass spectrometry-based quantitative proteomic analysis of ARPE19 cells, using stable-isotope labeling of amino acids in cell cu...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2024-01-26 | PXD035841 | Pride
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