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TranscriptomicsCarnitine palmitoyltransferase 1A (CPT1A): a transcriptional target of PAX3-FKHR and mediates PAX3-FKHR-dependent motility in alveolar rhabdomyosarcoma cells
Background: Alveolar rhabdomyosarcoma (ARMS) has a high propensity to metastasize, leading to its aggressiveness and a poor survival rate among those with the disease. More than 80% of aggressive ARMSs harbor a PAX3-FKHR fusion transcription factor, which regulates cell migration and promotes metast...
ORGANISM(S): Homo sapiens 
2012-05-15 | E-GEOD-35862 | biostudies-arrayexpress
ProteomicsCross-sectional study of proteomic differences between moderate and severe psoriasis
Background: Although there is an ongoing understanding of psoriasis vulgaris (PV) pathogenesis, little is known about the proteomic diversity of psoriatic lesions between moderate and severe psoriasis. Objective: To evaluate the proteomic differences between moderate and severe psoriasis and determi...
ORGANISM(S): Homo Sapiens 
PXD052886 |
ProteomicsLactylation of Hdac1 regulated by Ldh prevents the pluripotent-to-2C state conversion
Embryonic stem cells (ESCs) were labeled with heavy isotopes, 13C615N4-arginine (Arg10) and 13C614N2-lysine (Lys6), or light isotopes, 12C614N4-arginine (Arg0) and 12C614N2-lysine (Lys0), respectively, for a total of 7 passages to ensure efficient labeling (>97%). The ESCs labeled with heavy isotope...
ORGANISM(S): Mus Musculus 
PXD050051 |
ProteomicsProteotypic differences of follicular-patterned thyroid neoplasms
The diagnosis of follicular-patterned thyroid tumors such as follicular adenoma (FA), follicular thyroid carcinoma (FTC), and follicular variant of papillary thyroid carcinoma (FvPTC) remains challenging. This study aimed to explore the molecular differences among these three thyroid tumors by prote...
ORGANISM(S): Homo Sapiens 
2022-09-07 | PXD036553 |
ProteomicsPCSHA changhai prostate cancer (PCa) proteomics
We enrolled PCa patients to analysis proteomics and build a survival prediction model
ORGANISM(S): Homo Sapiens 
PXD054025 |
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