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MetabolomicsComprehensive Untargeted Metabolomics Dataset of Saccharomyces cerevisiae Aging-Associated Mutants and Yeast–Host Interactions in Drosophila melanogaster

Aging is a complex biological process influenced by genetic factors, environmental conditions, and interactions between organisms and their associated microbes. The budding yeast Saccharomyces cerevisiae and the fruit fly Drosophila melanogaster provide complementary model systems for investigati...

2026-09-04 | MTBLS15555 | MetaboLights
ProteomicsProteome of Yki-driven intestinal stem cell tumors in Drosophila midgut
The experiment was undertaken to characterize Yki-driven intestinal stem cell tumor proteome from Drosophila adult midguts, and to identify changes in the ISC tumor proteome in flies fed on TONDU peptide, using LC MS/MS approach. esgts>UAS-yki3SA flies on day 1, day 7 of tumor induction; TONDU-pepti...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2020-01-25 | MSV000084841 | MassIVE
ProteomicsProteome Plasticity in Drosophila Hybrids
This submission contains 3 different datasets: - series A: D. melanogaster female ? D. simulans male embryos vs internal standard of pooled D. simulans and D. melanogaster (1:1) embryos - series B: D. simulans female ? D. melanogaster male embryos vs internal standard of pooled D. simulans and D. m...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) Drosophila Simulans (ncbitaxon:7240) 
MSV000081535 | MassIVE
ProteomicsSpectral library of Drosophila melanogaster for SWATH-MS
A spectral library was built for Drosophila melanogaster. The spectral library allows reproducible quantification for thousands of peptides per SWATH-MS analysis. Proteins from Drosophila melanogaster embryo, adult flies were digested with trypsin using in-gel digestion and the peptides were fracti...
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) 
2017-05-11 | MSV000081075 | MassIVE
ProteomicsCharacterization of the redox proteome of Drosophila melanogaster S2 cells and w1118 fly eyes.
Reactive oxygen species (ROS) serve as intracellular signaling molecules; however, in excess ROS molecules are damaging to biomacromolecules such as DNA, lipids, and proteins. The excess accumulation of ROS leads to oxidative stress, disrupting redox homeostasis in the cell and has been linked with ...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-04-27 | PXD034050 | Pride
Drosophila melanogaster schneider s2 cells Drosophila eye Redox proteome Blue light 
ProteomicsDrosophila melanogaster LC-MSMS
we performed proteome sequencing in Drosophila at day 7 (young) and day 42 (old) under dietary restriction (DR)and ad libitum (AL) conditions.
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-09-09 | PXD021022 | Pride
Lc-msms Drosophila Plasma 
ProteomicsCharacterization of the redox proteome in Drosophila melanogaster aging eyes.
During oxidative stress, reactive oxygen species (ROS) can modify and damage cellular proteins. In particular, the thiol groups of cysteine residues can undergo reversible or irreversible oxidative post-translation modifications (PTMs). Identifying the redox-sensitive cysteines on a proteome-wide sc...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-04-27 | PXD036110 | Pride
Drosophila eye Oxidative post-translation modifications Redox proteome Aging 
TranscriptomicsRNAi profiling of Drosophila SL2 cells knocked down for ISWI
Profiling of changes in steady state RNA levels upon RNAi-mediated knockdown of the nucleosome remodeling ATPase ISWI in Drosophila SL2 cells. Quantitation of the corresponding proteomes has been performed to describe transcriptome-proteome relations. The analysis indicates a limited correlation of ...
ORGANISM(S): Drosophila melanogaster 
2008-10-25 | E-GEOD-11164 | biostudies-arrayexpress
TranscriptomicsRibosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster
Ribosomes can read through stop codons in a regulated manner, elongating rather than terminating the nascent peptide. Stop codon readthrough is essential to diverse viruses, and phylogenetically predicted to occur in a few hundred genes in Drosophila melanogaster, but the importance of regulated rea...
ORGANISM(S): Drosophila melanogaster 
2013-12-05 | E-GEOD-49197 | biostudies-arrayexpress
ProteomicsGene expression dynamics before and after zygotic gene activation in Drosophila early embryogenesis
Post-transcriptional gene regulatory mechanisms are fundamental to the determination of gene expression dynamics and especially crucial for the earliest stages of animal development in which transcription is nearly silent. Here we performed high-resolution total RNA-sequencing and quantitative mass ...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-09-08 | PXD057383 | Pride
Drosophila mzt development 
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