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A mass spectrometry-based proteomics analysis was performed to study the protein binders of DRSH-1 and PASH-1 in C. elegans.
ORGANISM(S): Escherichia coli Caenorhabditis elegans 
2025-03-13 | PXD052084 | Pride
Intermittent fasting (IF), a dietary restriction regimen, extends the lifespans of C. elegans and mammals by inducing gene expression changes. How fasting induces gene expression changes and longevity remains unclear. MicroRNAs (miRNAs) are small non-coding RNAs (approximately 22 nucleotides) that r...
ORGANISM(S): Caenorhabditis elegans 
2017-08-30 | GSE89614 | GEO
Intermittent fasting (IF), a dietary restriction regimen, extends the lifespans of C. elegans and mammals by inducing gene expression changes. How fasting induces gene expression changes and longevity remains unclear. MicroRNAs (miRNAs) are small non-coding RNAs (approximately 22 nucleotides) that r...
ORGANISM(S): synthetic construct Caenorhabditis elegans 
2017-08-30 | GSE89609 | GEO
Precise control of miRNA biogenesis is of extreme importance, since mis-regulation of miRNAs underlies or exacerbates many disease states. The Microprocessor complex, composed of DROSHA and DGCR8, carries out the first of two cleavage steps in canonical miRNA biogenesis. Despite recent advances in u...
ORGANISM(S): Caenorhabditis elegans 
2025-07-20 | GSE289120 | GEO
Role of the MicroRNA Machinery in Fasting-Induced Gene Expression Changes and Longevity in C. elegans (mRNA)
An intrinsically disordered region of Drosha selectively promotes miRNA biogenesis, independent of tissue-specific Microprocessor condensates
Role of the MicroRNA Machinery in Fasting-Induced Gene Expression Changes and Longevity in C. elegans (miRNA)
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