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ProteomicsQuantitative proteomics analysis reveals novel insights into mechanisms of action of Disulfiram (DSF)
The new uses of the old drugs may reduce cost and shortens the production cycle of research and development, especially that approved by FDA for important clinical conditions. Alcohol abuse Disulfiram (DSF) has been proven safe and shows the promising anti-tumor effect in may preclinical studies. H...
ORGANISM(S): Homo sapiens (Human) 
2021-11-27 | PXD024910 | Pride
Dsf  quantitative proteomics  migration  invasion 
TranscriptomicsA transcriptome study of DSF-mediated quorum sensing in Xanthomonas axonopodis pv. citri
Quorum sensing (QS) in Xanthomonas axonopodis pv. citri, the causal agent of citrus canker, is mediated by a diffusible signal factor (DSF). QS is required for the full virulence of X. axonopodis pv. citri in planta. Mutations in rpfF, rpfC and rpfG, the core genes of QS, decreased the production of...
ORGANISM(S): Xanthomonas axonopodis pv. citri str. 306 
2012-04-26 | E-GEOD-29877 | biostudies-arrayexpress
GenomicsDSF effects on Arabidopsis
DSF effects on Arabidopsis
PRJNA954814 | ENA
GenomicsExpression data from meningioma cell after DSF and Cu treatment
Expression data from meningioma cell after DSF and Cu treatment
PRJNA806864 | ENA
TranscriptomicsDSF effects on Arabidopsis
To investigate the effects of DSF on Arabidopsis in Xcc infecction, we used 2 μM DSF pretreated the roos of Arabidopsis for 48h and then inoculated with Xcc, We then performed gene expression profiling analysis using data obtained from RNA-seq of pretreated/unpretreated at two time points (inoculate...
ORGANISM(S): Arabidopsis thaliana 
2023-04-15 | GSE229511 | GEO
GenomicsThe impact of DSF and C23 on P. aeruginosa physiology
The impact of DSF and C23 on P. aeruginosa physiology
PRJNA432916 | ENA
TranscriptomicsThe impact of DSF and C23 on P. aeruginosa physiology
To verify the imapct of DSF and C23 on P. aeruginosa during infection We used microarray to compare the effects of adding either DSF alone or DSF with C23 on P. aeruginosa gene expression during mouse lung infection relative to the gene expression of P. aeruginosa in the mouse lung with no compound.
ORGANISM(S): Pseudomonas aeruginosa 
2018-09-30 | GSE110126 | GEO
TranscriptomicsExpression data from meningioma cell after DSF and Cu treatment
We demonstrate that DSF/Cu treatment reduced meningioma cell viability and increased intracellular ER stress. We used microarrays to analyze the DSF/Cu regulated gene expression.
ORGANISM(S): Homo sapiens 
2024-02-11 | GSE196689 | GEO
TranscriptomicsXanthomonas oryzae pv. oryzae (Indian Isolate): Wild type vs. rpfF mutant
Transcription profiling of the DSF regulon in Xanthomonas oryzae pv. oryzae (Xoo) using wild type and the rpfF mutant. Cell-cell signaling mediated by the quorum sensing molecule known as Diffusible Signaling factor (DSF) is required for virulence of Xanthomonas group of plant pathogens. DSF in diff...
ORGANISM(S): Xanthomonas oryzae pv. oryzae 
2011-04-02 | E-GEOD-27809 | biostudies-arrayexpress
TranscriptomicsXanthomonas oryzae pv. oryzicola (Indian Isolate) wild type and complented strains vs rpfF mutant grown under iron starved condition
Transcriptional profiling of DSF regulon under iron starvation in Xanthomonas oryzae pv. oryzicola (Xoc; BXOR1) using wild type, rpfF mutant and rpfF mutant with complementing plasmid pSC9. Cell-cell signalling mediated by quorum sensing molecule known as Diffusible signalling factor (DSF) is requir...
ORGANISM(S): Xanthomonas oryzae pv. oryzicola 
2015-01-02 | E-GEOD-53255 | biostudies-arrayexpress
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