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MetabolomicsLactobacillus reuteri DSM17938 and its supernatant ameliorate parkinson's disease: insights from multi-omics and network pharmacology

The mechanisms by which probiotics ameliorate neurodegenerative diseases have garnered significant scientific interest, yet elucidating their underlying pathways remains challenging. In this study, we establish an integrated multi-omics and network pharmacology strategy to unravel the prote...

2025-10-18 | MTBLS13169 | MetaboLights
TranscriptomicsPyrococcus furiosus DSM 3638 growth curve, tiling arrays
Experimentally mapped transcriptome structure of Pyrococcus furiosus DSM 3638 by hybridizing total RNA (including RNA species <200 nt) to genome-wide high-density tiling arrays (60 mer probes tiled every 16 nt). Pyrococcus furiosus DSM 3638 growth curve experiments were conducted in batch culture. R...
ORGANISM(S): Pyrococcus furiosus DSM 3638 
2011-06-27 | E-GEOD-26778 | biostudies-arrayexpress
TranscriptomicsExpression analysis of strains Lactococcus lactis KCTC 3769T, L. raffinolactis DSM 20443T, L. plantarum DSM 20686T, L. fujiensis JSM 16395T, L. garvieae KCTC 3772T, L. piscium DSM 6634T and L. chungangensis CAU 28T
Investigation of whole genome gene expression level changes in Lactococcus lactis KCTC 3769T,L. raffinolactis DSM 20443T, L. plantarum DSM 20686T, L. fujiensis JSM 16395T, L. garvieae KCTC 3772T, L. piscium DSM 6634T and L. chungangensis CAU 28T . This proves that transcriptional profiling can fac...
ORGANISM(S): Lactococcus piscium 
2014-05-28 | E-GEOD-58002 | biostudies-arrayexpress
ProteomicsAeromonas jandaei DSM 7311 secretome
Label-free quantification comparative proteomics analysis of proteins secreted to the media by Aeromonas jandaei DSM 7311 wild-type or its derivates in which the adhesins craAj or lapAj were deleted.
ORGANISM(S): Aeromonas jandaei 
2026-09-30 | PXD084964 | Pride
Aeromonas Adhesin Bacteria Secretome 
TranscriptomicsGenome-wide transcriptional profiling of the purple sulfur bacterium Allochromatium vinosum DSM 180T during growth on different reduced sulfur compounds [Set1]
The purple sulfur bacterium Allochromatium vinosum DSM 180T is one of the best studied sulfur-oxidizing anoxygenic phototrophic bacteria and has been developed into a model organism for laboratory-based studies of oxidative sulfur metabolism. Here, we took advantage of the organismM-bM-^@M-^Ys high ...
ORGANISM(S): Allochromatium vinosum DSM 180 
2013-07-29 | E-GEOD-44040 | biostudies-arrayexpress
TranscriptomicsGenome-wide transcriptional profiling of the purple sulfur bacterium Allochromatium vinosum DSM 180T during growth on different reduced sulfur compounds [Set2]
The purple sulfur bacterium Allochromatium vinosum DSM 180T is one of the best studied sulfur-oxidizing anoxygenic phototrophic bacteria and has been developed into a model organism for laboratory-based studies of oxidative sulfur metabolism. Here, we took advantage of the organismM-bM-^@M-^Ys high ...
ORGANISM(S): Allochromatium vinosum DSM 180 
2013-07-29 | E-GEOD-44041 | biostudies-arrayexpress
TranscriptomicsGene expression comparison of L. reuteri DSM 17938 and pocR mutant
Comparison of gene expression between L. reuteri DSM 17938 and L. reuteri DSM 17938::pocR mutant grown in semi-defined medium after 24h of growth at 37C in anaerobic condition. PocR is an AraC-like transcriptional regulator, and changes in gene expression between mutant and wild-type strains would...
ORGANISM(S): Lactobacillus reuteri 
2014-01-24 | E-GEOD-54324 | biostudies-arrayexpress
ProteomicsAeromonas jandaei DSM 7311 T6SS secretome - comparative proteomics
Label-free quantification comparative proteomics analysis of proteins secreted to the media by the T6SS of Aeromonas jandaei DSM 7311
ORGANISM(S): Aeromonas jandaei 
2024-08-13 | PXD054809 | Pride
Secretion Aeromonas Tssb Effector T6ss 
ProteomicsProteome analysis of Actinomycetospora chiangmaiensis DSM 45062 degrading 2-HIBA
The tertiary branched short-chain 2-hydroxyisobutyric acid (2-HIBA) has been associated with several metabolic diseases and lysine 2-hydroxyisobutyrylation seems to be a common eukaryotic as well as prokaryotic post-translational modification in proteins. In contrast, the underlying 2-HIBA metabolis...
ORGANISM(S): Actinomycetospora chiangmaiensis DSM 45062 
2020-03-17 | PXD017800 | Pride
Tert-butyl alcohol 2-hydroxyacyl-coa lyase Fuel oxygenate Degradation pathway Mycolicibacterium Isobutene Acyloin condensation 
ProteomicsProteomic analysis of Limosilactobacillus reuteri DSM 17938
The aim of this work was to assess the antibiofilm activity of Cell Free Supernatant (CFS) produced by Limosilactobacillus reuteri DSM 17938 versus biofilm-producer bacterial species of clinical relevance.
ORGANISM(S): Escherichia coli 
2025-06-09 | PXD035326 | Pride
Extracellular membrane vesicles Postbiotics Lactobacillus reuteri Cytotoxicity  metabolomics Probiotics Limosilactobacillus reuteri Antibiofilm activity Cell free supernatant 
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