Sort   by:  
 Page size 
MetabolomicsEnterobacter ludwigii protects DSS-induced colitis through choline-mediated immune tolerance
Commensal intestinal bacteria play key roles in regulating cells mediating immune tolerance; however, bacterial strains and related metabolites directly involved in this regulation are largely unknown. Here, using a mouse model of dextran sulfate sodium (DSS)-induced colitis combined with different ...
2024-08-05 | MTBLS5585 | MetaboLights
MetabolomicsMetabolomic profiling of zebrafish DSS-induced colitis intervened by Akkermansia muciniphila-derived extracellular vesicles (AmEVs)
This study performs untargeted metabolomics analysis on intestinal tissues of DSS-induced colitis zebrafish models to uncover the metabolic regulatory mechanisms of AmEVs. We compared intestinal metabolite profiles between two experimental groups: DSS-induced colitis model group and AmEV interventio...
2026-07-22 | MTBLS14855 | MetaboLights
MetabolomicsFecal short-chain fatty acids in DSS-induced colitis mice treated with a D-lactate-free probiotic
Targeted GC-MS quantification of short- and branched-chain fatty acids in feces of C57BL/6J (B6J-UniBe) mice with acute dextran sulfate sodium (DSS)-induced colitis. Mice received the D-lactate-free probiotic consortium Pro4-50 by daily oral gavage either from the start of the experiment (Pre, n=10)...
2026-10-08 | MTBLS15952 | MetaboLights
MetabolomicsBupleurum chinense DC polysaccharides ameliorate DSS-induced ulcerative colitis by regulating gut microbiota and tryptophan metabolism via NF-κB pathway

Background: Bupleurum chinense DC polysaccharide (BCP) demonstrates a significant role in ameliorating gastric ulceration and enhancing intestinal barrier function, and have broad medicinal value. Nevertheless, the therapeutic effects and mechanisms in ulcerative colitis (UC) remain to be elucida...

2026-02-01 | MTBLS13814 | MetaboLights
MetabolomicsUntargeted metabolomics of cecal contents from DSS induced colitis mice with and without Veillonella parvula colonization

Cecal contents metabolomics analysis of DSS-induced colitis mice and DSS-induced colitis mice with V. parvula colonization.

2025-08-12 | MTBLS12276 | MetaboLights
MetabolomicsGermacrone Protects Against DSS Induced Colitis Through a Gut Microbiota Derived Indole-3-Carboxylic Acid-AhR-ILC3/IL-22 Axis
Ulcerative colitis (UC) is a chronic recurrent inflammatory bowel disease, which is characterized by intestinal microbiota dysbiosis, intestinal barrier and mucosal immune dysfunction. Given the limited effect of biological agents for UC, there is an urgent need to develop more effective pharmacolog...
2026-08-30 | MTBLS15475 | MetaboLights
MetabolomicsMeasurements of fecal bile acids abundance in DSS induced UC mice model

Background and aims: Elevation of conjugated primary bile acid—GCA in fecal samples was reported in IBD patients compared to healthy controls (nearly 10-fold), as well as in active ulcerative colitis (UC) patients relative to those in remission stages. Therefore we wanted to investigate the poten...

2026-05-03 | MTBLS14031 | MetaboLights
MetabolomicsReactive Oxygen Species Deficiency Due to Ncf1-Mutation Leads to Development of Adenocarcinoma and Metabolomic and Lipidomic Remodeling in a New Mouse Model of Dextran Sulfate Sodium-Induced Colitis
Inflammatory bowel disease is characterized by chronic relapsing idiopathic inflammation of the gastrointestinal tract and persistent inflammation. Studies focusing on the immune-regulatory function of reactive oxygen species (ROS) are still largely missing. In this study, we analyzed an ROS-deficie...
2019-05-22 | MTBLS593 | MetaboLights
MetabolomicsMeasurements of fecal glycocholic acid abundance in DSS induced UC mice model treated with 200 mg per kg glycocholic acid

Background: Unlike the reported CA, the abundance of fecal GCA did not significantly increase after DSS treatment in C57BL/6J mice. Hence, exogenous supplementation of GCA were given to DSS-induced colitis mice via oral gavage. We want to know whether GCA treatment at 200 mg/kg yielded fecal GCA ...

2026-05-03 | MTBLS14032 | MetaboLights
MetabolomicsD-lactate-free probiotic treatment in colitis
Effect of the D-lactate free bacteria in DSS-induced colitis mouse model
2026-10-09 | MTBLS15974 | MetaboLights
Sort   by:  
 Page size