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ProteomicsProteomics of the brain and retina presents early hallmarks of Alzheimer’s disease
We performed proteomic profiling of the brain and retina in 3xTg-AD mouse model of Alzheimer's disease at one month of age to uncover early retinal signatures that may precede disease manifestations.
ORGANISM(S): Mus musculus (Mouse) 
2026-06-08 | PXD069995 | Pride
Alzheimer's disease  retina  brain  neurodegenerative diseases  3xtg-ad 
ProteomicsProteomic characterization of infant and adult ornithine aminotransferase-deficient mice
The deficiency of ornithine aminotransferase (OAT) cause gyrate atrophy, a progressive chorioretinal degeneration disease culminating in blindness. This project investigates age- and tissue-specific proteomic changes in the retina, retinal pigment epithelium (RPE), and liver of OAT-deficient mice to...
ORGANISM(S): Mus musculus (Mouse) 
2026-07-06 | PXD063614 | Pride
Ornithine Metabolism Ornithine aminotransferase Proteomics Gyrate atrophy Retina pigment epithelium Liver Oat Retina 
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