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TranscriptomicsTranscription profiling of irradiated non-adherent anoikis-resistant DU145 and MCF-7 cells and 5-azacytidine-treated non-adherent anoikis-resistant HeLa cells in contrast to control (non-irradiated, non-treated) cells.
Radiation and chemotherapy represent standard-of-care cancer treatments, however most treated patients eventually experience tumor recurrence, treatment failure and metastatic dissemination with fatal consequences. To elucidate molecular mechanisms of resistance to radio- and chemo-therapy, we expos...
ORGANISM(S): Homo sapiens 
2018-07-01 | E-MTAB-6062 | biostudies-arrayexpress
TranscriptomicsMultiscale spatial mapping of cell populations across anatomical sites in healthy human skin and basal cell carcinoma - Spatial Transcriptomics - 10X Visium
Our understanding of how human skin cells differ according to anatomical site and tumour formation is limited. To address this we have created a multi-scale spatial atlas of healthy skin and basal cell carcinoma (BCC), incorporating in vivo optical coherence tomography, single cell RNA sequencing, s...
ORGANISM(S): Homo sapiens 
2023-12-22 | E-MTAB-13085 | biostudies-arrayexpress
UnknownAssociations of Renalase With Blood Pressure and Hypertension in Chinese Adults.
Not available
S-EPMC8907541 | biostudies-literature
TranscriptomicsA profibrotic gene expression program induced by Egr-1 in skin fibroblasts
Systemic sclerosis (SSc) is characterized by vascular damage, autoimmunity and fibrosis and is associated with highly variable clinical presentation and disease course. Aberrant transforming growth factor-ß (TGF-ß) signaling via the early immediate transcription factor Egr-1 is implicated in the pat...
ORGANISM(S): Homo sapiens 
2011-10-25 | E-GEOD-27165 | biostudies-arrayexpress
UnknownAssociations of Long-Term Visit-to-Visit Blood Pressure Variability With Subclinical Kidney Damage and Albuminuria in Adulthood: a 30-Year Prospective Cohort Study.
Not available
S-EPMC9093226 | biostudies-literature
TranscriptomicsPathogenic Keratinocyte States and Fibroblast Niches Define the Tissue Microenvironment in Severe Hidradenitis Suppurativa
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by recurrent painful abscesses and tunnels in flexural sites. The mechanisms driving HS pathogenesis, particularly the interactions between epithelial, stromal and immune cell populations, remain incompletely understo...
ORGANISM(S): Homo sapiens 
2026-07-12 | E-MTAB-17238 | biostudies-arrayexpress
UnknownSARS-CoV-2 hijacks neutralizing dimeric IgA for nasal infection and injury in Syrian hamsters1.
Not available
S-EPMC10444022 | biostudies-literature
UnknownEffect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.
Not available
S-EPMC8491132 | biostudies-literature
UnknownCanadian Surgery Forum.
Not available
S-EPMC3432251 | biostudies-literature
UnknownThe database of the PREDICTS (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems) project.
Not available
S-EPMC5215197 | biostudies-literature
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