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MetabolomicsDual metal electrolysis in theta capillary for lipid analysis

Increasing studies associating glycerophospholipids with various pathological conditions highlight the need for their thorough characterization. However, the intricate composition of the lipidome due to the presence of lipid isomers poses significant challenges to structural lipidomics. This stud...

2023-10-10 | MTBLS8547 | MetaboLights
MetabolomicsDigital Phenomics and Dual-Fluid Metabolomics for Precision Stratification of Diabetic Kidney Disease: A Multicenter Cohort Study

We conducted a prospective-retrospective two-center cohort study involving 364 participants. The Discovery Cohort (n=282) enrolled from two centers consisted of healthy controls (n=80), patients with type 2 diabetes mellitus (T2DM) without kidney disease (n=102), and patients with confirmed DKD (...

2026-03-09 | MTBLS14007 | MetaboLights
MetabolomicsGlycosylation-mediated detoxification of zearalenone by the Tibetan yeast Hannaella zeae: Multi-omics insights into its dual-function mechanism

This study investigated the detoxification of zearalenone (ZEN) by the Tibetan Plateau yeast Hannaella zeae via untargeted LC-MS/MS-based metabolomics. H. zeae was cultured in NYDB medium with ZEN supplementation, and samples were harvested after 36 h of incubation for metabolomic analysis. The c...

2026-08-20 | MTBLS15233 | MetaboLights
ProteomicsEvaluation of a Dual Isolation Width Acquisition (DIWA) method for isobaric labelling ratio decompression
Stable isotope labelling of peptides using isobaric reagents such as iTRAQ and TMT enables the multiplexed analysis of proteomes with deep quantitative coverage. Isobaric tagging demonstrates high precision but imperfect accuracy due to ratio underestimation caused by co-fragmentation of ions with m...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2019-01-07 | PXD010571 | Pride
Method development Tmt Msms Diwa 
ProteomicsPeptide standard acquired with the dual-gated SLIM-Orbitrap
Raw data collected on the dual-gated SLIM-Orbitrap. The sample contained a mixture of standard peptides at 1 uM equimolar concentration in 60:40 water:acetonitrile with 1% acetic acid (v/v). The peptides were kemptide, angiotensin I, bradykinin, neurotensin, angiotensin II, renin substrate tetradeca...
ORGANISM(S): Peptide Standards 
2023-08-23 | MSV000092738 | MassIVE
UnknownMS1 Peptide Ion Intensity Chromatograms in MS2 (SWATH) Data Independent Acquisitions. Improving Post Acquisition Analysis of Proteomic Experiments.
Not available
S-EPMC4563724 | biostudies-literature
UnknownEvaluating UV-C LED disinfection performance and investigating potential dual-wavelength synergy.
Not available
S-EPMC6145099 | biostudies-literature
ProteomicsMS1 Peptide Ion Intensity Chromatograms in MS2 (SWATH) Data Independent Acquisitions
Quantitative analysis of discovery-based proteomic workflows now relies on high-throughput large-scale methods for identification and quantification of proteins and post-translational modifications. Advancements in label-free quantitative techniques, using either data-dependent or data-independent m...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2015-04-01 | MSV000079092 | MassIVE
ProteomicsOptimization of dual-column LC system and comparison of RTLS vs standard MS2 approach via healthy donor PBMC samples
This is the second of three MassIVE repositories associated with the manuscript "Single-Cell Proteomics of Human Peripheral Blood Mononuclear Cells Exceeding 600 Cells per Day." This repository contains TMTpro 32-plex-labeled datasets from a healthy human PBMC donor, including both bulk (10 ng) and ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2026-01-31 | MSV000100683 | MassIVE
ProteomicsDual Preconditioned Mesenchymal Stem Cells-Derived Secretome Augment Immunomodulation and Drive Metabolic Reprogramming in Acute Graft-versus-Host Disease
The immune plasticity of the host critically influences disease progression and therapeutic outcomes. In acute graft-versus-host disease (aGVHD), conventional conditioning regimens often induce toxicity, underscoring the need for effective adjunctive strategies to restore immune balance. This study ...
ORGANISM(S): Homo sapiens (Human) 
2026-05-04 | PXD077957 | Pride
Immunomodulation Antioxidant Metabolic shift Tissue repair Apoptosis Secretome Mesenchymal stem cells Acute graft-versus-host-disease Hypoxia 
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