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Department of Molecular Pathology and Biology, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic (1)
Dr. Roman Fischer Associate Professor and Head of Discovery Proteomics Facility University of Oxford Target Discovery Institute, NDMRB Roosevelt Drive Oxford, OX3 7FZ United Kingdom (1)
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Evotec München GmbH Am Klopferspitz 19a 82152 Planegg (1)
Fujian Provincial Key Laboratory of Plant Functional Biology, Fujian Agriculture and Forestry University, Fuzhou 350002, China (1)
Harvard Medical School Boston, MA 02115, USA (1)
Institute of Immunology, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany (1)
Leiden Univeristy Medical Center (1)

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Transcriptomics following CRISPR KO of individual DUBs or inhibition of DUBs with small molecule inhibitors

PRJNA777261 | ENA

Deubiquitinases (DUBs) and DUB inhibitors: a patent review.

Not available

S-EPMC4834700 | biostudies-literature

Transcriptomics following CRISPR KO of individual DUBs or inhibition of DUBs with small molecule inhibitors

CRISPR KO RNA-seq data: To generate knockouts, we used a commercially available arrayed CRISPR-Cas9 library targeting 81 out of ~100 DUBs and 13 additional proteins in the ubiquitin-proteasome system, including ubiquitin-like proteins; the library was constructed with four, pooled, guides per target...

ORGANISM(S): Homo sapiens

2021-11-03 | GSE187008 | GEO

The emerging role of Deubiquitinases (DUBs) in parasites: A foresight review.

Not available

S-EPMC9552668 | biostudies-literature

Molecular Mechanisms of DUBs Regulation in Signaling and Disease.

Not available

S-EPMC7863924 | biostudies-literature

CRISPR DUBs screen beta1 Integrin surface level

PRJNA1146728 | ENA

A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Not available

S-EPMC4762628 | biostudies-literature

Redox regulation of DUBs and its therapeutic implications in cancer.

Not available

S-EPMC8608616 | biostudies-literature

Fission yeast DUB substrates - A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival

His-Biotin-His Ubiquitin was overexpressed in various fission yeast (S. pombe) genetic backgrounds to identify ubiqutinated proteins. Normalizing to bait (ubiquitin) across samples provided insight into relative changes in ubiquitination with loss of deubiquitinases (DUBs), yielding putative DUB sub...

ORGANISM(S): Schizosaccharomyces pombe

2017-06-09 | PXD001767 | Pride

Ubiquitin deubiquitinases fission yeast ubiquitination

DUBs Activating the Hedgehog Signaling Pathway: A Promising Therapeutic Target in Cancer.

Not available

S-EPMC7352588 | biostudies-literature

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