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To better understand mechanisms of cell organization and function in the aortas of healthy and MFS patients, we performed single cell RNA sequencing (scRNA-seq) and label-free single-cell mass spectrometry35 in aortas isolated from healthy and MFS mice and human MFS aneurysm aortic tissue. We discov...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-09-14 | PXD078860 | Pride
Mass spectrometry was performed using aortic tissue from patients with Marfan syndrome or healthy controls and from a mouse model of Marfan syndrome (Fbn1 C1041G/+) or wild-type controls to validate single-cell proteomics.
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-09-14 | PXD079005 | Pride
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