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ProteomicsHigh-resolution proteomic analysis of medulloblastoma clinical samples identifies therapy resistant subgroups and MYC immunohistochemistry as a powerful outcome predictor
While international consensus and the 2021 WHO classification recognize multiple molecular medulloblastoma subgroups, these are difficult to identify in current clinical practice. As a result, biology driven risk stratification and therapy assignment for medulloblastoma constitutes a major challenge...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD051235 | Pride
Proteomics Medulloblastoma Myc Immunohistochemistry 
ProteomicsHigh-resolution proteomic analysis of medulloblastoma clinical samples identifies therapy resistant subgroups and MYC immunohistochemistry as a powerful outcome predictor
While international consensus and the 2021 WHO classification recognize multiple molecular medulloblastoma subgroups, these are difficult to identify in current clinical practice. As a result, biology driven risk stratification and therapy assignment for medulloblastoma constitutes a major challenge...
ORGANISM(S): Homo sapiens (Human) 
2025-03-06 | PXD051319 | Pride
Medulloblastoma Dia Proteomics Myc Immunohistochemistry 
TranscriptomicsPediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes
Rhabdoid tumors (RTs) are aggressive tumors of early childhood that occur most often in brain (AT/RTs) or kidney (KRTs). Regardless of location, they are characterized by loss of functional SMARCB1 protein, a component of the SWI/SNF chromatin remodeling complex. The aim of this study was to determi...
ORGANISM(S): Homo sapiens 
2013-01-21 | E-GEOD-35493 | biostudies-arrayexpress
UnknownTherapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.
Not available
S-EPMC4962737 | biostudies-literature
TranscriptomicsUsing transient nondisjunction to generate disomic strains of yeast
Background. Most methods for constructing aneuploid yeast strains that have gained a specific chromosome rely on spontaneous failures of cell division fidelity. In Saccharomyces cerevisiae, extra chromosomes can be obtained when errors in meiosis or mitosis lead to nondisjunction, or when nuclear br...
ORGANISM(S): Saccharomyces cerevisiae 
2009-01-13 | E-GEOD-14377 | biostudies-arrayexpress
TranscriptomicsHigh expression of BMP pathway genes distinguishes a subset of Atypical Teratoid/Rhabdoid Tumors associated with shorter survival
Molecular profiling of tumors has proven a valuable tool for identification of prognostic and diagnostic subgroups in medulloblastomas, glioblastomas and other cancers. However, the molecular landscape of atypical teratoid / rhabdoid tumors (AT/RTs) remains largely unexplored. To address this issue,...
ORGANISM(S): Homo sapiens 
2011-09-21 | E-GEOD-28026 | biostudies-arrayexpress
GenomicsSMG
Severe malaria cases from Gambia
EGAD00000000018 | EGA
GenomicsCBC
Cord blood control samples from Gambia
EGAD00000000017 | EGA
GenomicsMalariaGEN case-control study in the Gambia
MalariaGEN case-control study in the Gambia.
EGAS00000000026 | EGA
GenomicsMalariaGEN data access committee
Access to individual-level genotype data is available by application to the MalariaGEN Independent Data Access Committee. Access to data will be granted to qualified investigators for appropriate use. For further information information on data release policy and data access application form, please...
EGAC00000000002 | EGA
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