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ProteomicsTranscription factors induce differential splicing of duplicated ribosomal protein genes during meiosis
In Saccharomyces cerevisiae, most ribosomal proteins are produced from duplicated genes. These nearly identical protein pairs are expressed at varying levels, with one ‘major paralog’ usually predominating. The minor paralog is highly transcribed but held in check through reduced intron removal, but...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-12-20 | PXD050249 | Pride
Splicing Ribosomal proteins Yeast 
ProteomicsLeishmania Ribosomal Protein (RP) paralogous genes compensate each other’s expression maintaining protein native levels
We investigated the potential compensatory mechanism and possibility of noncanonical function of ribosomal proteins encoded by duplicated genes in Leishmania major.
ORGANISM(S): Leishmania major 
2024-06-03 | PXD047334 | Pride
Ribosomal proteins Compensatory mechanism. Duplicated genes Gene expression 
TranscriptomicsRNA-seq analysis of alternative splicing events in duplicated genes of Arabidopsis thaliana indicates considerable qualitative and quantitative divergence
Divergence of alternative splicing in duplicated genes is investigated Three replicates of RNA-seq for Arabidopsis first true leaf tissue
ORGANISM(S): Arabidopsis thaliana 
2014-09-30 | E-GEOD-57579 | biostudies-arrayexpress
ProteomicsDuplicated ribosomal protein paralogs promote alternative translation and drug resistance
Ribosomes are often seen as monolithic machines produced from uniformly regulated genes. However, in yeast most ribosomal proteins come from duplicated genes. Here, we demonstrate that gene duplication may serve as a stress-adaptation mechanism modulating the global proteome through the differential...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-08-09 | PXD033843 | Pride
Drpg Saccharomyces cerevisiae Paralogs 
TranscriptomicsEvolutionary Diversification of Duplicated Genes; Experiment J
This study measured the rates at which duplicated genes in the Daphnia pulex genome diverge in function, based on significant differences in their gene expression when paralogs of various ages were tested across 8 to 12 contrasting conditions. The conditions were designated A to L. The number and d...
ORGANISM(S): Daphnia pulex 
2011-02-01 | E-GEOD-25850 | biostudies-arrayexpress
TranscriptomicsEvolutionary Diversification of Duplicated Genes; Experiment A
This study measured the rates at which duplicated genes in the Daphnia pulex genome diverge in function, based on significant differences in their gene expression when paralogs of various ages were tested across 8 to 12 contrasting conditions. The conditions were designated A to L. The number and d...
ORGANISM(S): Daphnia pulex 
2011-02-01 | E-GEOD-25841 | biostudies-arrayexpress
UnknownDoes the Presence of Transposable Elements Impact the Epigenetic Environment of Human Duplicated Genes?
Not available
S-EPMC6470583 | biostudies-literature
TranscriptomicsEvolutionary Diversification of Duplicated Genes; Experiments B-I
This study measured the rates at which duplicated genes in the Daphnia pulex genome diverge in function, based on significant differences in their gene expression when paralogs of various ages were tested across 8 to 12 contrasting conditions. The conditions were designated A to L. The number and d...
ORGANISM(S): Daphnia pulex 
2011-02-01 | E-GEOD-25845 | biostudies-arrayexpress
TranscriptomicsEvolutionary Diversification of Duplicated Genes; Experiment L, K
This study measured the rates at which duplicated genes in the Daphnia pulex genome diverge in function, based on significant differences in their gene expression when paralogs of various ages were tested across 8 to 12 contrasting conditions. The conditions were designated A to L. The number and d...
ORGANISM(S): Daphnia pulex 
2011-02-01 | E-GEOD-25851 | biostudies-arrayexpress
UnknownPervasive and persistent redundancy among duplicated genes in yeast.
Not available
S-EPMC2440806 | biostudies-literature
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