Sort   by:  
 Page size 
TranscriptomicsRegulatory Mutations Affecting Sulfur Metabolism Induce Environmental Stress Response in Aspergillus nidulas
Mutations in the cysB, sconB and sconC genes affect sulfur metabolism in Aspergillus nidulans in different ways. Mutation of cysB blocks synthesis of cysteine by the main pathway leaving only the less effective alternative route. Mutations of sconB or sconC affect subunits of the SCF ubiquitin ligas...
ORGANISM(S): Aspergillus nidulans 
2014-02-14 | E-GEOD-54130 | biostudies-arrayexpress
UnknownComplete Genome Sequences of Microbacterium Phages Clayda5 and Gshelby23 and Gordonia Phages Wrigley and Santhid.
Not available
S-EPMC9670969 | biostudies-literature
TranscriptomicsTcRBP40 pull-down ribonomics
RNA pull-down assay.
For the recombinant protein pull-down assays, 50 M-5g of recombinant His-tag TcRBP40 protein were bound to 100 uL of Ni-NTA resin (Qiagen) overnight at 4M-0C. 100 M-5g of total RNA from epimastigotes were incubated with the bound protein in 500 M-5l EMSA buffer at 4M-0C for 2...
ORGANISM(S): Trypanosoma cruzi 
2012-06-30 | E-MEXP-3057 | biostudies-arrayexpress
TranscriptomicsRosR is a haloarchaeal-specific transcription factor required for the response to extreme oxidative stress in Halobacterium salinarum NRC-1.
Previous work has shown that the hypersaline-adapted archaeon, Halobacterium salinarum NRC-1, is highly resistant to oxidative stress caused by exposure to hydrogen peroxide, UV and gamma radiation. Genome-wide dynamics alteration of gene the GRN has been implicated in such resistance. However, the...
ORGANISM(S): Halobacterium sp. NRC-1 
2012-08-12 | E-GEOD-33980 | biostudies-arrayexpress
TranscriptomicsThe metalloregulatory site in Streptococcus pneumoniae AdcR, a zinc-activated MarR-family repressor
Streptococcus pneumoniae D39 AdcR (adhesion competence repressor) is the first metal-sensing member of the MarR (multiple antibiotic resistance repressor) family to be characterized. Expression profiling of a ∆adcR strain grown in liquid culture under microaerobic conditions revealed that transcr...
ORGANISM(S): Streptococcus pneumoniae 
2010-10-01 | E-GEOD-21506 | biostudies-arrayexpress
ProteomicsAntibody microarray profiling of pancreatic cancer using 12 urine samples
Antibody microarray based profiling of twelve urine samples.
3 healthy female
3 heatlhy male
3 female with pancreatic cancer
3 male with pancreatic cancer
ORGANISM(S): Homo sapiens 
2012-05-03 | E-MEXP-3006 | biostudies-arrayexpress
TranscriptomicsThe effects of timing of fine needle aspiration biopsies on gene expression profiles in breast cancers
Paired fine needle aspiration biopsies (FNABs) of breast cancers were taken before (PRE) and after (POST) surgeries from 16 patients and compared the cDNA microarray data to determine the genes that were differentially expressed between the FNABs taken at the two time points. The timing of fine need...
ORGANISM(S): Homo sapiens 
2008-09-09 | E-GEOD-12072 | biostudies-arrayexpress
TranscriptomicsIpsA, a novel transcriptional regulator required for inositol derived lipid formation in Corynebacteria and Mycobacteria
The development of new drugs against tuberculosis and diphtheria is focused on disrupting the biogenesis of the cell wall, the unique architecture of which confers resistance against current therapies. The enzymatic pathways involved in the synthesis of the cell wall by these pathogens are well unde...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2014-01-13 | E-GEOD-50210 | biostudies-arrayexpress
UnknownT-cell CX3CR1 expression as a dynamic blood-based biomarker of response to immune checkpoint inhibitors.
Not available
S-EPMC7930182 | biostudies-literature
TranscriptomicsAn Artificial miRNA Against HSPE Suppresses Melanoma Invasion Properties Correlating with a Down-regulation of Chemokines and MAPK Phosphorylation
Heparanase (HPSE) is an endo-beta-glucuronidase that can cleave heparan sulfate proteoglycans within extracellular matrix, basement membrane or on the cellular surface, closely linked with proliferation, migration, invasion and angiogenesis of tumor cells, and has become a hot treatment target in an...
ORGANISM(S): Homo sapiens 
2012-10-27 | E-MEXP-3443 | biostudies-arrayexpress
Sort   by:  
 Page size