Sort   by:  
 Page size 
ProteomicsMudPIT analyses of the human proteins biotinylated by proximity to dynein/dynactin subunits fused to biotin ligase (BioID)
We identified the human dynein proteome by attaching a promiscuous biotin ligase (BioID) to 7 distinct components of the dynein machinery, including a subunit of its essential cofactor dynactin. BioID experiments were performed with stable HEK293 cell lines expressing dynein (IC1, IC2, LIC1, LIC2, R...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080759 | MassIVE
ProteomicsMudPIT analyses of the human proteins biotinylated by proximity to biotin ligase (BioID) fused to the N-terminus of activators of the dynein/dynactin motor
To capture the spatial organization of the dynein/dynactin motor, we attached a promiscuous biotin ligase (BioID) to 6 distinct activators of the dynein machinery motile activity. BioID experiments were performed with stable HEK293 cell lines expressing full length BICD1, BICD2, HOOK1, HOOK3, NIN an...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-30 | MSV000080807 | MassIVE
ProteomicsMudPIT analyses of the human proteins biotinylated by proximity to biotin ligase (BioID) fused to the C-terminus of activators of the dynein/dynactin motor
To understand how a single motor achieves cargo specificity, we attached a promiscuous biotin ligase (BioID) to 6 distinct activators of the dynein machinery motile activity, including two new activators, ninein and ninein-like. BioID experiments were performed with stable HEK293 cell lines expressi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-30 | MSV000080808 | MassIVE
ProteomicsCrosslinking/mass spectrometry (CLMS) analysis of Tetrahymena ODA-Q22MS1 complex
The outer dynein arms (ODAs) are the main force generators in cilia. Crosslinking/mass spectrometry (CLMS) was applied to investigate the interaction between ODA and its binding factor Q22MS1.
ORGANISM(S): Tetrahymena 
2021-12-07 | PXD022936 | JPOST Repository
ProteomicsProtein interactions with HA-tagged cytoplasmic dynein-2 DATASET2
To identify those proteins interacting with the cytoplasmic dynein-2 using mammalian cell lines stably expressing HA-tagged intermediate chain subunits, WDR34 (DYNC2I2) or WDR60 (DYNC2I1).
ORGANISM(S): Homo sapiens (Human) 
2023-01-24 | PXD031152 | Pride
Dynein-2 Cilia Intraflagellar transport 
ProteomicsProtein interactions with HA-tagged cytoplasmic dynein-2 DATASET1
To identify those proteins interacting with the cytoplasmic dynein-2 using mammalian cell lines stably expressing HA-tagged intermediate chain subunits, WDR34 (DYNC2I2) or WDR60 (DYNC2I1).
ORGANISM(S): Homo sapiens (Human) 
2023-01-24 | PXD031151 | Pride
Dynein-2 Cilia Intraflagellar transport 
ProteomicsProtein interactions with HA-tagged cytoplasmic dynein-2 DATASET2
To identify those proteins interacting with the cytoplasmic dynein-2 using mammalian cell lines stably expressing HA-tagged intermediate chain subunits, WDR34 (DYNC2I2) or WDR60 (DYNC2I1).
ORGANISM(S): Homo sapiens (Human) 
2023-01-24 | PXD031153 | Pride
Dynein-2 Cilia Intraflagellar transport 
ProteomicsProtein interactions with HA-tagged cytoplasmic dynein-2 DATASET1
To identify those proteins interacting with the cytoplasmic dynein-2 using mammalian cell lines stably expressing HA-tagged intermediate chain subunits, WDR34 (DYNC2I2) or WDR60 (DYNC2I1).
ORGANISM(S): Homo sapiens (Human) 
2023-01-24 | PXD031154 | Pride
Dynein-2 Cilia Intraflagellar transport 
ProteomicsIsoform-specific Patterns of Phosphorylation on Axonemal Dynein Heavy Chains
Axonemal dyneins power ciliary motility and phosphorylation of key intermediate and light chain components affects the regulation and properties of these motors in very distantly related organisms. It is also known that many axonemal dynein heavy chains are subject to this post-translational modific...
ORGANISM(S): Chlamydomonas sp. HS-5 
2025-04-25 | PXD061468 | Pride
Dynein Axoneme Chlamydomonas Phosphorylation 
ProteomicsDisease-associated mutations in WDR34 lead to diverse impacts on the assembly and function of dynein-2
The primary cilium is a sensory organelle, receiving signals from the external environment and relaying them into the cell. Mutations in proteins required for transport in the primary cilium lead to ciliopathies, a group of genetic disorders that commonly lead to the malformation of organs such as t...
ORGANISM(S): Homo sapiens (Human) 
2024-04-15 | PXD046827 | Pride
Human Cilia Dynein-2 
Sort   by:  
 Page size