Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of mouse embryonic stem cells with a doxycycline-inducible Xist cDNA transgene introduced into chromosome 17
A doxycycline-inducible Xist cDNA transgene was introduced into mouse chromosome 17 at approximately 71.24Mb (NCBI Build m36). Insertion of the transgene was heterozygous, so only one copy of chromosome 17 carried the transgene, and the other chromosome 17 was wild-type. Upon doxycycline induction...
ORGANISM(S): Mus musculus 
2010-05-10 | E-MEXP-2087 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fibroblast-like synovial cells from normal adult horse following treatment with hyaluronan and challenged with lipopolysaccharide
Greater than 95% confluent (Day 0) fibroblast-like synovial cells from the hind limbs (pelvic limb) of normal adult horses were allocated in triplicate to one of 4 groups:

(group 1) unchallenged;
(group 2) LPS-challenged;
(group 3) LPS-challenged following pre-treatment and susta...
ORGANISM(S): Equus caballus 
2007-01-10 | E-MEXP-940 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of homozygous Commd1 null mouse embryos to elucidate the underlying mechanism leading to embryonic lethality
A gene expression study using microarray analysis was performed to elucidate the underlying mechanism leading to embryonic lethality in homozygous Commd1 null (Commd1-/-) mouse embryos. A gene expression profile of 9.5 dpc Commd1-/- embryos were generated and were compared to a gene expression profi...
ORGANISM(S): Mus musculus 
2006-09-01 | E-MEXP-832 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryonic stem cells with a doxycycline-inducible Xist cDNA transgene introduced into chromosome 3
A doxycycline-inducible Xist cDNA transgene was introduced into mouse chromosome 3 at approximately 99.79Mb (NCBI Build m36). Insertion of the transgene was homozygous, so only one copy of chromosome 3 carried the transgene, and the other chromosome 3 was wild-type. Upon doxycycline induction, the...
ORGANISM(S): Mus musculus 
2010-05-10 | E-MEXP-2086 | biostudies-arrayexpress
TranscriptomicsMycobacterial infection induces a specific human innate immune response
The innate immune system provides the first response to pathogen infection and orchestrates the activation of the adaptive immune system. Though a large component of the innate immune response is common to all infections, pathogen-specific innate immune responses have been documented as well. The in...
ORGANISM(S): Homo sapiens 
2015-03-31 | E-GEOD-67427 | biostudies-arrayexpress
TranscriptomicsTetracycline-Inducible Cyr61 effect on LN229 glioma cells
Glioblastoma multiforme is the most common and aggressive form of brain cancer. The use of oncolytic HSV-1 (oHSV) to selectively target brain cancer cells leading to their lytic destruction has shown to be very promising in a preclinical setting, but is lacking efficacy in clinical trials. Cyr61, a ...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-29384 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat severed medial collateral ligament following injury
Gene Expression Profiling of Severed Rat Medial Collateral Ligament at 1, 2, 4, 7,1 0, and 14 days Following Injury with Control and Cultured Ligament Fibroblasts and Rat Universal Reference RNA; The aim of this study was to assess the genes involved in the repair of the the dense connective tissue ...
ORGANISM(S): Rattus norvegicus 
2008-04-05 | E-GEOD-10720 | biostudies-arrayexpress
TranscriptomicsDiversity in the polyadenylation and decay of human cellular microRNAs during Vaccinia virus infection
Vaccinia virus (VACV) is a large cytoplasmic dsDNA virus that causes dramatic alterations to many cellular pathways including microRNA biogenesis. Here we use small RNA sequencing to comprehensively quantify the impact of VACV infection on the expression of endogenous small non-coding RNAs (sncRNAs)...
ORGANISM(S): Homo sapiens 
2015-07-15 | E-GEOD-54235 | biostudies-arrayexpress
TranscriptomicsICL010 - Infection of Calu-3 cells with H1N1 influenza virus A/Netherlands/602/2009
Differential expression was determined in Calu-3 cells between mock infected and infected with H1N1 influenza virus A/Netherlands/602/2009 at nine time points post-infection. As a comparison, cells were also infected with A/CA/04/2009 H1N1 influenza virus at 4 time points post-infection. Cells were ...
ORGANISM(S): Homo sapiens 
2012-09-13 | E-GEOD-40844 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression analysis of the effects of a parasitic nematode's secreted exosomes on mammalian cells.
We show that a gastrointestinal nematode that infects mice, Heligmosomoides polygyrus, secretes vesicles packaged with specific microRNAs (miRNAs) and Y RNAs as well as a nematode-specific Argonaute protein. The vesicles are of intestinal origin and are enriched for homologs of mammalian proteins fo...
ORGANISM(S): Mus musculus 
2014-12-24 | E-GEOD-55941 | biostudies-arrayexpress
Sort   by:  
 Page size