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GenomicsComparative analysis of TAL1 binding in TSA-treated versus non-treated Endothelial Colony Forming Cells (ECFCs)
Endothelial progenitors represent one of the most promising cell-based strategies for vascular repair of ischemic tissue damage, including limb ischemia, myocardial infarction and stroke. We have shown that the transcription factor TAL1 regulates a transcription program that drives the migration and...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-53423 | biostudies-arrayexpress
ProteomicsCardiovascular-related proteomic changes in ECFCs exposed to the serum of COVID-19 patients
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection not only exerts a deep impact over the respiratory system, but it also affects the cardiovascular system, causing vascular damage and thromboembolic events in critical patients. The endothelial dysfunction taking place in respons...
ORGANISM(S): Homo sapiens (Human) 
2023-03-20 | PXD034620 | Pride
Covid-19 Viral infection Mass spectrometry Rna metabolism Ecfcs 
TranscriptomicsshRNA mediated knock-down of Tal1 in human Endothelial Colony Forming Cells (ECFCs)
Endothelial colony-forming cells (ECFCs) have been reported as promising cells for regenerative medicine thanks to their angiorepair properties. Transcription factors are primary determinants of the functional capacity of the cells and TAL1 has been shown as a critical regulator of endothelial linea...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-44444 | biostudies-arrayexpress
TranscriptomicsHuman umbilical cord blood-derived endothelial colony forming cells under serum-free conditions
Derivation and expansion of human umbilical cord blood-derived endothelial colony forming cells under serum-free conditions - a transcriptome analysis. Endothelial colony forming cells (ECFCs) were isolated from term umbilical cord blood units. ECFCs were expanded under standard, fetal bovine serum ...
ORGANISM(S): Homo sapiens 
2010-07-29 | E-GEOD-20504 | biostudies-arrayexpress
ProteomicsUnraveling the differential mechanisms of revascularization promoted by MSCs & ECFCs from adipose tissue or umbilical cord in a murine model of critical limb-threatening ischemia.
Critical limb threatening ischemia (CLTI), the most severe manifestation of peripheral artery disease, results from the chronic blockade of peripheral vessels, usually induced by atherosclerosis. CLTI patients suffer from high risk of amputation of the lower extremities and elevated mortality rates,...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-25 | PXD046843 | Pride
Mscs Critical limb-threatening ischemia Proteomics Cell therapy Adipose tissue Ecfcs 
TranscriptomicsProspective surface marker-based isolation and expansion of fetal endothelial colony-forming cells from human term placenta.
The term placenta is a highly vascularized tissue and is usually discarded upon birth. Our objective was to isolate clinically relevant quantities of fetal endothelial colony-forming cells (ECFCs) from human term placenta and to compare them to the well-established donor-matched umbilical cord blood...
ORGANISM(S): Homo sapiens 
2015-03-02 | E-MTAB-3277 | biostudies-arrayexpress
GenomicsHuman ECFCs: Cord Blood vs Peripehral Blood ECFCs
miRNA profiling was carried out using the miRCURY LNA™ microRNA Array (5th gen - hsa, mmu & rno). microRNA profiling of CB and PB-derived ECFCs from 3 independent donors from each cell source. To identify and understand the regulation of endothelial cell functions through comparing miRNA expression ...
ORGANISM(S): Rattus norvegicus Homo sapiens Mus musculus 
2017-03-20 | GSE81574 | GEO
GenomicsGenomic binding profile of TAL1 in human Endothelial Colony-Forming Cells
Endothelial colony-forming cells (ECFCs) have been reported as promising cells for regenerative medicine thanks to their angiorepair properties. Transcription factors are primary determinants of the functional capacity of the cells and TAL1 has been shown as a critical regulator of endothelial linea...
ORGANISM(S): Homo sapiens 
2014-05-06 | E-GEOD-44442 | biostudies-arrayexpress
GenomicsHomo sapiens
Human ECFCs: Cord Blood vs Peripehral Blood ECFCs
PRJNA322029 | ENA
GenomicsGene expression profile of Endothelial colony-forming cells (ECFCs) isolated from patients with unprovoked venous thromboembolism (uVTE)
Gene expression profile of Endothelial colony-forming cells (ECFCs) isolated from patients with unprovoked venous thromboembolism (uVTE)
PRJNA484968 | ENA
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