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nudt7-1 mutant plant exhibit stunted growth, enhanced basal resistance, elevated SA levels and spontaneous leaf cell death that is restricted to single cells but does not spread. All of these phenotypes depend on EDS1, a key regulator of plant innate immunity. Moreover, SA depletion in nudt7-1 resul...
ORGANISM(S): Arabidopsis thaliana 
Gene expression profiling leading to the identification of novel components in the EDS1/PAD4-regulated defence pathway
ORGANISM(S): Arabidopsis thaliana 
Nod-like receptors (NLRs) belong to AAA+ ATPases and act as ATP-dependent molecular switches, which detect activity of pathogens. Function of a large class of plant NLRs with Toll-like domain (TNL) is fully dependent on a class of EDS1-like proteins specific to seed plants. EDS1 (Enhanced Disease Su...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-04-06 | PXD025202 | Pride
Transcriptome analysis of EDS1-R493A after Pst AvrRps4- triggered immunity
Transcriptome analysis of EDS1 4h after Pst AvrRps4- triggered immunity
Arabidopsis pathogen effector-triggered immunity (ETI) is controlled by a family of three lipase-like proteins EDS1, PAD4 and SAG101 and two sub-families of HET-S/LOB-B (HeLo)-domain “helper” NLRs, ADR1s and NRG1s. EDS1-PAD4 dimers cooperate with ADR1s, and EDS1-SAG101 dimers with NRG1s, in two sepa...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-03-17 | PXD029477 | Pride
TIR-type nucleotide-binding leucine-rich repeat domain proteins (TNLs) constitute one major group of immune receptors in dicotyledonous plants. Under normal conditions, TNLs can detect non-self or modified-self within the plant cytoplasm to activate immune signaling characterized by extensive transc...
ORGANISM(S): Arabidopsis thaliana 
2017-02-09 | GSE65415 | GEO
Innate immune responses of plant cells confer the first line of defence against pathogens. Signals generated by activated receptors are integrated inside the cell and converge on transcriptional programmes in the nucleus. The Arabidopsis Toll-related intracellular receptor RPS4 operates inside nucle...
ORGANISM(S): Arabidopsis thaliana 
There is growing evidence that for a comprehensive insight into the function of plant genes it is crucial to assess their functionalities under a wide range of conditions. In this study we examined the role of LESION SIMULATING DISEASE1 (LSD1), ENHANCED DISEASE SUSCEPTIBILITY1 (EDS1) and PHYTOALEXIN...
ORGANISM(S): Arabidopsis thaliana 
Arabidopsis does not support the growth and asexual reproduction of the barley pathogen, Blumeria graminis f. sp. hordei Bgh). A majority of germlings fail to penetrate the epidermal cell wall and papillae. To gain additional insight into this interaction, we determined whether the salicylic acid (S...
ORGANISM(S): Arabidopsis thaliana 
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