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Our aim was to find an effective treatment for the dysfunction in energy regulation and hypothalamic integrity occurring in many HuntingtonM-bM-^@M-^Ys disease (HD) patients and mouse models. HD is a neurodegenerative disease caused by an expanded CAG repeat and is characterized by mutant huntingtin...
ORGANISM(S): Mus musculus 
Calorie restriction (CR) is the most robust non-genetic intervention to universally delay the onset of age-related diseases and extend mean and maximum lifespan. However, species, strain, sex, diet, age of onset, and level of CR are emerging as important variables to consider for a successful CR res...
ORGANISM(S): Mus musculus 
The goal of this project was to compare the extracellular matrix (ECM) composition – or matrisome – of CD8-high (“hot’) and CD8-low (“cold”) subcutaneous murine pancreatic ductal adenocarcinomas
ORGANISM(S): Mus musculus (Mouse) 
2026-04-30 | PXD060932 | Pride
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