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TranscriptomicsResponse and adaptation to growth with low glucose concentration
The faecal indicator bacterium Escherichia coli K12 was used to study the cellular events that take place at the transcription level using the microarray technology during short-term (physiological) and long-term (genetic) adaptation to slow growth under limited nutrient supply. Short-term and long-...
ORGANISM(S): Escherichia coli 
2010-07-01 | E-GEOD-4706 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of environmental Escherichia coli isolates indicates highly conserved ecophysiology
Escherichia coli, the common inhabitant of the mammalian intestine, exhibits considerable intraspecies genomic variation, which has been suggested to reflect adaptation to different ecological niches. Also, regulatory trade-offs, e.g., between catabolic versatility and stress protection, are thought...
ORGANISM(S): Escherichia coli 
2006-12-04 | E-GEOD-6407 | biostudies-arrayexpress
TranscriptomicsIdentification of promoter sequence elements involved in specific recognition by the ?S subunit of bacterial RNA polymerase.
Promoter recognition by bacterial RNA polymerase is mediated by ? subunits, which assemble transiently to RNA polymerase core enzyme (E) during transcription initiation. ? subunits drive transcription of specific sets of genes by allowing RNA polymerase to interact with different promoter sequences....
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2011-05-31 | E-GEOD-22207 | biostudies-arrayexpress
UnknownIL-28B is a key regulator of B- and T-cell vaccine responses against influenza.
Not available
S-EPMC4263767 | biostudies-literature
TranscriptomicsEffect of the global regulators RpoS and cyclic-AMP/CRP on the transcriptome of Escherichia coli K12 during carbon- and energy-limited growth
The faecal indicator bacterium Escherichia coli K12 was used to study the effects of the global regulators RpoS and cAMP at the transcription level using microarray technology during short-term (physiological) adaptation to slow growth under limited nutrient supply. Effects due to the absence of one...
ORGANISM(S): Escherichia coli K-12 
2010-12-16 | E-GEOD-25982 | biostudies-arrayexpress
TranscriptomicsGenome-wide transcription analysis of Escherichia coli in response to extremely low-frequency magnetic fields
The widespread use of electricity raises the question of whether or not 50 Hz (power line frequency in Europe) magnetic fields (MFs) affect organisms. We investigated the transcription of Escherichia coli K-12 MG1655 in response to extremely low-frequency (ELF) MFs. Fields generated by three signal ...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2012-01-28 | E-GEOD-35371 | biostudies-arrayexpress
UnknownA MALDI-TOF MS library for rapid identification of human commensal gut bacteria from the class Clostridia.
Not available
S-EPMC9990839 | biostudies-literature
UnknownIFNΛ3/4 locus polymorphisms and IFNΛ3 circulating levels are associated with COPD severity and outcomes.
Not available
S-EPMC5861655 | biostudies-literature
TranscriptomicsBRCT phosphoprotein recognition, but not E3 ligase activity, is essential for BRCA1 tumor suppression
It has been recognized that BRCA1, in the form of the BRCA1/BARD1 heterodimer, acting as an ubiquitin E3 ligase offered a possible mechanism to explain its pleiotrophic nature of BRCA1 activity. Our observation that mice lacking BRCA1 enzymatic activity are viable apart from male sterility was unex...
ORGANISM(S): Mus musculus 
2011-08-25 | E-GEOD-31673 | biostudies-arrayexpress
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