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TranscriptomicseIF3a in Urinary Bladder Cancer M-bM-^@M-^S in vivo and in vitro insights
The eukaryotic translation initiation factor (eIF) 3a is described in various tumor entities as potential tumor marker involved in development and progression of cancer. eIF3a is the largest subunit of the eIF3 complex, a key functional entity in 80S establishment and translation initiation. We hypo...
ORGANISM(S): Homo sapiens 
2014-08-12 | E-GEOD-45636 | biostudies-arrayexpress
ProteomicsProteomic profiling of eIF3a conditional knockout mice
In this study, a Cre-loxP system was used to generate eIF3a conditional knockout mice. Tandem mass tag (TMT) labeling with LC-MS/MS analysis was used to identify differentially expressed proteins (DEPs) in fat, lungs, skin, and spleen tissue of the eIF3a knockout mice and controls. Bioinformatics an...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD041416 | Pride
Eif3a Proteomics Knockout mice Protein landscape Oxidative stress 
Transcriptomicsm6A in 5’ untranslated regions promotes cap-independent translation of mRNA
N6-methyladenosine (m6A) is a widespread internal RNA modification whose function is poorly understood. Here we report that m6A residues within the 5'UTR promote a novel form of cap-independent translation which is mediated through an interaction between m6A residues and the translation initiation f...
ORGANISM(S): Homo sapiens 
2015-10-26 | E-GEOD-73405 | biostudies-arrayexpress
GenomicsMETTL16, eIF3a and eIF3b binding transcripts in HepG2 liver cancer cells [RIP-seq]
METTL16, eIF3a and eIF3b binding transcripts in HepG2 liver cancer cells [RIP-seq]
PRJNA929295 | ENA
TranscriptomicseIF3a in Urinary Bladder Cancer – in vivo and in vitro insights
The eukaryotic translation initiation factor (eIF) 3a is described in various tumor entities as potential tumor marker involved in development and progression of cancer. eIF3a is the largest subunit of the eIF3 complex, a key functional entity in 80S establishment and translation initiation. We hypo...
ORGANISM(S): Homo sapiens 
2014-08-12 | GSE45636 | GEO
GenomicsCancer associated mRNAs regulated by the Helix Loop Helix motif of human EIF3A
Cancer associated mRNAs regulated by the Helix Loop Helix motif of human EIF3A
PRJNA484941 | ENA
UnknownCircular RNA screening from EIF3a in lung cancer.
Not available
S-EPMC6675731 | biostudies-literature
OtherMETTL16, eIF3a and eIF3b binding transcripts in HepG2 liver cancer cells [RIP-seq]
To investigate the specific binding transcripts of METTL16, eIF3a and eIF3b in liver cancer cells, we established HepG2 cell lines following METTL16, eIF3a and eIF3b overexpression. We then performed RNA Immunoprecipitation (RIP) in HepG2 cells, and both the input and immunoprecipitated RNA were use...
ORGANISM(S): Homo sapiens 
2024-01-30 | GSE224009 | GEO
GenomicsDynamic O-GlcNAcylation of eIF3a controls translation reinitiation during integrated stress response
Dynamic O-GlcNAcylation of eIF3a controls translation reinitiation during integrated stress response
PRJNA750456 | ENA
UnknowneIF3a Regulates Colorectal Cancer Metastasis via Translational Activation of RhoA and Cdc42.
Not available
S-EPMC8921074 | biostudies-literature
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