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GenomicsSerratia plymuthica strain:EIF4
Serratia plymuthica strain:EIF4 Genome sequencing
PRJNA1233243 | ENA
GenomicsSerratia plymuthica strain:EIF4
Serratia plymuthica strain:EIF4 Genome sequencing
PRJNA1443069 | ENA
UnknownGenetic evidence supporting potential causal roles of EIF4 family in breast cancer: a two-sample randomized Mendelian study.
Not available
S-EPMC11364806 | biostudies-literature
GenomicsIncreased competition for eIF4 factors or 40S ribosomal subunits disfavors translation preinitiation complex assembly on poorly translated mRNAs with high G/A nucleotide ratios in 5’ leaders [Rec-Seq]
Increased competition for eIF4 factors or 40S ribosomal subunits disfavors translation preinitiation complex assembly on poorly translated mRNAs with high G/A nucleotide ratios in 5’ leaders [Rec-Seq]
PRJNA1334203 | ENA
TranscriptomicsmRNA Sequencing of skeletal muscle genes in wildtype and BCATm (BCAT2) KO mice
Consumption of a protein containing meal by a fasted animal promotes protein accretion in skeletal muscle, in part through leucine stimulation of protein synthesis and indirectly through repression of protein degradation mediated by its metabolite, α-ketoisocaproate. Mice lacking the mitochondrial ...
ORGANISM(S): Mus musculus 
2015-12-11 | E-GEOD-68915 | biostudies-arrayexpress
TranscriptomicsIncreased competition for eIF4 factors or 40S ribosomal subunits disfavors translation preinitiation complex assembly on poorly translated mRNAs with high G/A nucleotide ratios in 5’ leaders [Rec-Seq]
The ribosome concentration model (RCM) posits that deprivation of ribosomal subunits reprograms translation to favor mRNAs with high initiation rates. We tested the RCM using the yeast reconstituted initiation system by measuring PIC assembly on all native mRNAs in parallel (Rec-Seq) at different 40...
ORGANISM(S): Saccharomyces cerevisiae BY4741 Saccharomyces cerevisiae 
2026-04-13 | GSE309137 | GEO
UnknownThe 5'-7-methylguanosine cap on eukaryotic mRNAs serves both to stimulate canonical translation initiation and to block an alternative pathway.
Not available
S-EPMC2945613 | biostudies-literature
UnknownRecruitment of the 40S ribosome subunit to the 3'-untranslated region (UTR) of a viral mRNA, via the eIF4 complex, facilitates cap-independent translation.
Not available
S-EPMC4416834 | biostudies-literature
ProteomicsInhibition of mPGES-1 or COX-2 Results in Different Proteomic and Lipidomic Profiles in A549 Lung Cancer Cells
We compared the effects of mPGES-1 inhibitor Compound III (CIII) with the cyclooxygenase (COX)-2 inhibitor NS-398 on protein and lipid profiles in interleukin (IL)-1β induced A549 lung cancer cells using mass spectrometry. Inhibition of mPGES-1 decreased PGE2 production and increased PGF2α and throm...
ORGANISM(S): Homo sapiens (Human) 
2019-05-20 | PXD013490 | Pride
Inflammation A549 Cancer Mpges-1 Lc-ms/ms 
UnknownReduced protein synthesis in schizophrenia patient-derived olfactory cells.
Not available
S-EPMC4930119 | biostudies-literature
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