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TranscriptomicsmRNAs translated at eIF4F
Identification of eukaryotic mRNAs that are translated at reduced cap binding complex eIF4F concentrations using a cDNA microarray. Although most eukaryotic mRNAs need a functional cap binding complex eIF4F for efficient 5' end-dependent scanning to initiate translation, picornaviral, hepatitis C vi...
ORGANISM(S): Homo sapiens 
2002-06-27 | E-GEOD-62 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mRNAs that remained associated with polysomes isolated from human cells after infection with poliovirus
Although most eukaryotic mRNAs need a functional cap binding complex eIF4F for efficient 5' end- dependent scanning to initiate translation, picornaviral, hepatitis C viral, and a few cellular RNAs have been shown to be translated by internal ribosome entry, a mechanism that can operate in the prese...
ORGANISM(S): Homo sapiens 
2005-06-24 | E-SMDB-59 | biostudies-arrayexpress
GenomicsInhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex [A549]
Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex [A549]
PRJNA814884 | ENA
GenomicsInhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex [Vero E6]
Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex [Vero E6]
PRJNA814883 | ENA
GenomicsTargeting the translation complex eIF4F disrupts BCR::ABL1 tranlstion and overcomes drug resistance in CML
Targeting the translation complex eIF4F disrupts BCR::ABL1 tranlstion and overcomes drug resistance in CML
PRJNA1478893 | ENA
TranscriptomicsmTORC1 and CK2 coordinate ternary and eIF4F complex assembly
mRNA translation plays a major role in homeostasis, whereas its dysregulation underpins a variety of pathological states including cancer, metabolic syndrome and neurological disorders. Ternary complex (TC) and eIF4F complex assembly are two major rate-limiting steps in translation initiation that a...
ORGANISM(S): Homo sapiens 
2016-04-01 | GSE76766 | GEO
UnknownInhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex.
Not available
S-EPMC9751428 | biostudies-literature
GenomicsTargeting eIF4F Translation Initiation Complex with SBI-756 Sensitizes B Lymphoma Cells to Venetoclax
Targeting eIF4F Translation Initiation Complex with SBI-756 Sensitizes B Lymphoma Cells to Venetoclax
PRJNA670855 | ENA
ProteomicsTwo distinct Trypanosoma eIF4F complexes co-exist, bind different mRNAs and are regulated during nutritional stress
Many eIF4F subunits and PABP paralogues are found in trypanosomes: six eIF4E, five eIF4G, one eIF4A and two PABPs. They are expressed simultaneously and assemble into different complexes, contrasting the situation in metazoans that use distinct complexes in different cell types or developmental stag...
ORGANISM(S): Trypanosoma cruzi Dm28c 
2025-05-06 | PXD051440 | Pride
Nutritional stress Trypanosoma Eif4f Translation initiation 
UnknownmTORC1 and CK2 coordinate ternary and eIF4F complex assembly.
Not available
S-EPMC4822005 | biostudies-literature
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