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ProteomicsMouse EL4 Tumor Proteome Comparison via LC-MSMS
The EL4 mouse tumor model is widely utilized within the field of oncology due to its ease of use and excellent response to chemotherapy, with tumors typically experiencing a reduction in mass of 70% following chemotherapy treatment with cyclophosphamide and etoposide for three days. As not much is k...
ORGANISM(S): Mus musculus (Mouse) 
2017-05-19 | PXD005592 | Pride
Chemotherapy Mouse tumor Tumor death El4 lymphoma Proteomics 
GenomicsNext Generation Sequencing Facilitates Quantitative Analysis of EL4+Ctrl and EL4+RGFP966 cells' Transcriptomes in T cells lymphoma
Next Generation Sequencing Facilitates Quantitative Analysis of EL4+Ctrl and EL4+RGFP966 cells' Transcriptomes in T cells lymphoma
PRJNA1017862 | ENA
ProteomicsLC-MSMS of the EL4 MHC class I, immunopeptidome
MHC I-associated peptides (MAPs) presented at the surface of nucleated cells play a central role in CD8 T-cell immunosurveillance. MAPs presented by mature (i.e. MHC IIhi) medullary thymic epithelial cells (mTEChi) are essential to eliminate self-reactive CD8 T cells in a process called central tole...
ORGANISM(S): Mus musculus (Mouse) 
2018-10-22 | PXD009064 | Pride
Lc-msms Mouse Immunopeptidome Cell line Mhc class i 
UnknownDifferential expression of FAK and Pyk2 in metastatic and non-metastatic EL4 lymphoma cell lines.
Not available
S-EPMC3193847 | biostudies-literature
TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of EL4+Ctrl and EL4+RGFP966 cells' Transcriptomes in T cells lymphoma
We here reported that HDAC3 inhibition induces the infiltration of NK cells in lymphoma and enhances their cytotoxicity by promoting the secretion of CXCL12 from lymphoma cells. RNA-seq analysis of EL4 cells treated with or without RGFP966 showed that chemokine signaling was significantly enriched i...
ORGANISM(S): Mus musculus 
2024-04-18 | GSE243346 | GEO
TranscriptomicsGene expression changes following demethylation by 5-aza-2'-deoxycytidine（decitabine, DAC）in mouse T cell lymphoma EL4 cells
Our study had shown that DAC treatment enhanced immunogenecity of EL4 cells. To explore the mechanisms of DAC-induced tumor immunity, we carried out cDNA microarray analyses to compare the differential expression of genes between DAC and PBS treated EL4 cells. Two-condition experiment, PBS treated E...
ORGANISM(S): Mus musculus 
2013-02-15 | E-GEOD-38473 | biostudies-arrayexpress
UnknownDifferential Expression of Ccn4 and Other Genes Between Metastatic and Non-metastatic EL4 Mouse Lymphoma Cells.
Not available
S-EPMC5219917 | biostudies-literature
GenomicsGene expression analysis of 83A25-stimulated EL4 cells
Gene expression analysis of 83A25-stimulated EL4 cells
PRJEB36787 | ENA
TranscriptomicsRNA-seq of mouse EL4 cells overexpressing Israa gene product in comparison with Mock-transfected control cells
Israa is an intron nested gene involved in the regulation of T-cell activation in mice. This experiment investigates the differential expression of genes in T-cell line overexpressing israa ORF compared to mock transfected cells
ORGANISM(S): Mus musculus 
2018-07-15 | E-MTAB-6979 | biostudies-arrayexpress
UnknownCombined α-programmed death-1 monoclonal antibody blockade and fractionated radiation therapy reduces tumor growth in mouse EL4 lymphoma.
Not available
S-EPMC6605991 | biostudies-literature
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