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TranscriptomicsTranscription profiling of muscle and liver tissue in collagen-induced arthritis (CIA) and control mice treated with increasing doses of prednisolone
Prednisolone is a potent anti-inflammatory glucocorticoid (GC) but chronic use is hampered by metabolic side effects. Although GCs are predominantly prescribed for treatment of inflammatory conditions, little is known about their long-term effects on gene-expression in-vivo during inflammation. Here...
ORGANISM(S): Mus musculus 
2013-11-10 | E-MTAB-1765 | biostudies-arrayexpress
MetabolomicsMetabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor (Untargeted urine, plasma and liver NMR assay)
BACKGROUND: Epidemiological evidence suggests a link between pesticide exposure and the development of metabolic diseases. However, most experimental studies have evaluated the metabolic effects of pesticides using individual molecules, often at non-relevant doses or in combination with other r...
2018-05-01 | MTBLS602 | MetaboLights
MetabolomicsTitanium dioxide in food induces sex- and microbiota-dependent metabolic disorders, and worsens high-fat diet outcomes
Ultra-processed food consumption has been linked to the rising global burden of metabolic diseases, but the specific contribution of additives commonly used in these products remains unclear. Given the bactericidal properties of the food-grade (fg) additive titanium dioxide (TiO2) and the key role o...
2026-05-19 | MTBLS14529 | MetaboLights
TranscriptomicsMicroarray of liver samples from male mice fed a Western-diet or a Chow diet enriched with 9% of cellulose or inulin
The aim is to look the effect of dietary fibers (cellulose or inulin) on the hepatic transcriptome of mice fed either a western diet (WD) or a chow diet (CD). C57Bl/6J male mice aged 8 weeks were housed at thermoneutrality (TN, 30°C) and fed a WD or a CD during 17 weeks. CD and WD were supplemented ...
ORGANISM(S): Mus musculus 
2026-01-01 | E-MTAB-16279 | biostudies-arrayexpress
MetabolomicsMetabolic Effects of a Chronic Dietary Exposure to a Low-Dose Pesticide Cocktail in Mice: Sexual Dimorphism and Role of the Constitutive Androstane Receptor (Untargeted urine UPLC-MS assay)
BACKGROUND: Epidemiological evidence suggests a link between pesticide exposure and the development of metabolic diseases. However, most experimental studies have evaluated the metabolic effects of pesticides using individual molecules, often at non relevant doses or in combination with other r...
2019-05-28 | MTBLS596 | MetaboLights
TranscriptomicsEffect of hepatocyte-restricted deletion of fgf21 deletion on liver gene expression in response to fasting in mice
FGF21 is a liver-derived hormone potently induced in response to fasting. However, its role in the regulation of hepatic gene expression is unknown. The effect of 20h fasting on liver gene expression was investigated in wild-type mice and in mice lacking hepatocyte FGF21. Fgf21 hepatocyte-specific ...
ORGANISM(S): Mus musculus 
2026-10-16 | E-MTAB-15848 | biostudies-arrayexpress
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